Area of research
Physiology · Genetics
Research interest
Research interests include Alzheimer's disease research and treatments, Genetic Associations and Epidemiology, Bioinformatics and Genomic Networks, and Dementia and Cognitive Impairment Research.
Alzheimer's Disease Sequencing Project release 4 whole genome sequencing dataset
Novel modelling approaches to elucidate the genetic architecture of resilience to Alzheimer’s disease
Genome‐wide association studies of TDP‐43 proteinopathy and hippocampal sclerosis reveal shared genetic associations with APOE and TMEM106B
Copy Number Variation and Haplotype Analysis of <scp>17q21.31</scp> Reveals Increased Risk Associated with Progressive Supranuclear Palsy and Gene Expression Changes in Neuronal Cells
Report of the APOE4 National Institute on Aging/Alzheimer Disease Sequencing Project Consortium Working Group: Reducing APOE4 in Carriers is a Therapeutic Goal for Alzheimer's Disease
Whole-genome sequencing analysis reveals new susceptibility loci and structural variants associated with progressive supranuclear palsy
Extended genome‐wide association study employing the African genome resources panel identifies novel susceptibility loci for Alzheimer's disease in individuals of African ancestry
Association of common and rare variants with Alzheimer's disease in more than 13,000 diverse individuals with whole‐genome sequencing from the Alzheimer's Disease Sequencing Project
Asian Cohort for Alzheimer's Disease (ACAD) pilot study on genetic and non‐genetic risk factors for Alzheimer's disease among Asian Americans and Canadians
A genome-wide search for pleiotropy in more than 100,000 harmonized longitudinal cognitive domain scores
Sex‐specific genetic architecture of late‐life memory performance
DNA from multiple viral species is associated with Alzheimer's disease risk
Longitudinal change in memory performance as a strong endophenotype for Alzheimer's disease
Genetic, transcriptomic, histological, and biochemical analysis of progressive supranuclear palsy implicates glial activation and novel risk genes
Whole-Genome Sequencing Analysis Reveals New Susceptibility Loci and Structural Variants Associated with Progressive Supranuclear Palsy
A haptoglobin (HP) structural variant alters the effect of <i>APOE</i> alleles on Alzheimer's disease
The Early‐Onset Alzheimer's Disease Whole‐Genome Sequencing Project: Study design and methodology
Exome sequencing identifies rare damaging variants in ATP8B4 and ABCA1 as risk factors for Alzheimer’s disease
Sex differences in the genetic architecture of cognitive resilience to Alzheimer’s disease
A locus at 19q13.31 significantly reduces the ApoE ε4 risk for Alzheimer’s Disease in African Ancestry
Statistical and functional convergence of common and rare genetic influences on autism at chromosome 16p
Genome‐wide association and multi‐omics studies identify <i>MGMT</i> as a novel risk gene for Alzheimer's disease among women
Protein phosphatase 2A and complement component 4 are linked to the protective effect of <i>APOE</i> ɛ2 for Alzheimer's disease
Progranulin mutations in clinical and neuropathological Alzheimer's disease
Neuropathological lesions and their contribution to dementia and cognitive impairment in a heterogeneous clinical population
Admixture mapping identifies novel Alzheimer's disease risk regions in African Americans
TSC1 loss increases risk for tauopathy by inducing tau acetylation and preventing tau clearance via chaperone-mediated autophagy
Association of mitochondrial variants and haplogroups identified by whole exome sequencing with Alzheimer's disease
Large‐scale sequencing studies expand the known genetic architecture of Alzheimer's disease
The Asian Cohort for Alzheimer’s Disease (ACAD) study