Area of research
Genetics · Molecular Biology
Research interest
Research interests include Genetic Associations and Epidemiology, Alzheimer's disease research and treatments, Bioinformatics and Genomic Networks, and Epigenetics and DNA Methylation.
Alzheimer's Disease Sequencing Project release 4 whole genome sequencing dataset
Blood DNA methylation signature for incident dementia: Evidence from longitudinal cohorts
Novel early‐onset Alzheimer‐associated genes influence risk through dysregulation of glutamate, immune activation, and intracellular signaling pathways
DNA methylation signature of a lifestyle-based resilience index for cognitive health
Genome‐wide association studies of TDP‐43 proteinopathy and hippocampal sclerosis reveal shared genetic associations with APOE and TMEM106B
Extended genome‐wide association study employing the African genome resources panel identifies novel susceptibility loci for Alzheimer's disease in individuals of African ancestry
Blood-derived mitochondrial DNA copy number is associated with Alzheimer disease, Alzheimer-related biomarkers and serum metabolites
Association of common and rare variants with Alzheimer's disease in more than 13,000 diverse individuals with whole‐genome sequencing from the Alzheimer's Disease Sequencing Project
Critical evaluation of the reliability of DNA methylation probes on the Illumina MethylationEPIC v1.0 BeadChip microarrays
Associations of Sex, Race, and Apolipoprotein E Alleles With Multiple Domains of Cognition Among Older Adults
Explainable machine learning aggregates polygenic risk scores and electronic health records for Alzheimer’s disease prediction
Distinct CSF biomarker-associated DNA methylation in Alzheimer’s disease and cognitively normal subjects
Sex‐specific genetic architecture of late‐life memory performance
Identification of novel genes for age‐at‐onset of Alzheimer's disease by combining quantitative and survival trait analyses
DNA from multiple viral species is associated with Alzheimer's disease risk
Longitudinal change in memory performance as a strong endophenotype for Alzheimer's disease
A haptoglobin (HP) structural variant alters the effect of <i>APOE</i> alleles on Alzheimer's disease
ADSP Whole Genome Sequencing (WGS) Release 4 Data Update from Genome Center for Alzheimer’s Disease
Exome sequencing identifies rare damaging variants in ATP8B4 and ABCA1 as risk factors for Alzheimer’s disease
Cross-tissue analysis of blood and brain epigenome-wide association studies in Alzheimer’s disease
Genome‐wide association and multi‐omics studies identify <i>MGMT</i> as a novel risk gene for Alzheimer's disease among women
Admixture Mapping of Alzheimer’s disease in Caribbean Hispanics identifies a new locus on 22q13.1
Distinct sex-specific DNA methylation differences in Alzheimer’s disease
MethReg: estimating the regulatory potential of DNA methylation in gene transcription
Manifestations of Alzheimer’s disease genetic risk in the blood are evident in a multiomic analysis in healthy adults aged 18 to 90
Progranulin mutations in clinical and neuropathological Alzheimer's disease
Neuropathological lesions and their contribution to dementia and cognitive impairment in a heterogeneous clinical population
Admixture mapping identifies novel Alzheimer's disease risk regions in African Americans
Additional file 2 of Distinct sex-specific DNA methylation differences in Alzheimer’s disease
Sex-specific DNA methylation differences in Alzheimer’s disease pathology