Area of research
Genetics · Physiology
Research interest
Research interests include Alzheimer's disease research and treatments, Genetic Associations and Epidemiology, Parkinson's Disease Mechanisms and Treatments, and Dementia and Cognitive Impairment Research.
<i>APOE</i> and Alzheimer's disease and related dementias risk among 12,221 Hispanics/Latinos
Comparing Alzheimer's genes in African, European, and Amerindian induced pluripotent stem cell–derived microglia
Generalizability of tau and amyloid plasma biomarkers in Alzheimer's disease cohorts of diverse genetic ancestries
Alzheimer disease is (sometimes) highly heritable: Drivers of variation in heritability estimates for binary traits, a systematic review
Ancestral genomic functional differences in oligodendroglia: implications for Alzheimer's disease
Country-level incidence of Alzheimer disease and related dementias is associated with increased omega-6-PUFA consumption
<i>ABCA7</i> deletion lowers age at onset of Alzheimer's disease and interacts with <i>APOE</i> ε4 synergistically in African‐ancestry populations
The 2022 symposium on dementia and brain aging in low‐ and middle‐income countries: Highlights on research, diagnosis, care, and impact
Report of the APOE4 National Institute on Aging/Alzheimer Disease Sequencing Project Consortium Working Group: Reducing APOE4 in Carriers is a Therapeutic Goal for Alzheimer's Disease
Extended genome‐wide association study employing the African genome resources panel identifies novel susceptibility loci for Alzheimer's disease in individuals of African ancestry
A multi-region single nucleus transcriptomic atlas of Parkinson’s disease
Genome-wide association analysis and admixture mapping in a Puerto Rican cohort supports an Alzheimer disease risk locus on chromosome 12
Novel Stop-gain SORL1 Mutation in a Peruvian Family with Alzheimer’s Disease of the PeADI Study (P6-9.017)
African Ancestry Individuals with Higher Educational Attainment Are Resilient to Alzheimer’s Disease Measured by pTau181
Ancestry‐related differences in chromatin accessibility and gene expression of <i>APOE</i> ε4 are associated with Alzheimer's disease risk
A locus at 19q13.31 significantly reduces the ApoE ε4 risk for Alzheimer’s Disease in African Ancestry
Mutant C. elegans mitofusin leads to selective removal of mtDNA heteroplasmic deletions across generations to maintain fitness
Identifying differential regulatory control of <i>APOE</i> ɛ4 on African versus European haplotypes as potential therapeutic targets
Admixture mapping identifies novel Alzheimer's disease risk regions in African Americans
Using Oligodendrocytes for studies in Alzheimer disease
Increased <i>APOE</i> ε4 expression is associated with the difference in Alzheimer's disease risk from diverse ancestral backgrounds
Genomewide Association Studies of <scp> <i>LRRK2</i> </scp> Modifiers of Parkinson's Disease
A novel duplication involving <i>PRDM13</i> in a Turkish family supports its role in North Carolina macular dystrophy (NCMD/MCDR1).
PubMed 2021cited by 14position: middle
Dissecting the role of Amerindian genetic ancestry and the ApoE ε4 allele on Alzheimer disease in an admixed Peruvian population
Lower Levels of Education Are Associated with Cognitive Impairment in the Old Order Amish
Use of local genetic ancestry to assess <i>TOMM40</i> -523′ and risk for Alzheimer disease
Immune and Inflammatory Pathways Implicated by Whole Blood Transcriptomic Analysis in a Diverse Ancestry Alzheimer’s Disease Cohort
Genome-wide brain DNA methylation analysis suggests epigenetic reprogramming in Parkinson disease
RNA editing alterations in a multi-ethnic Alzheimer disease cohort converge on immune and endocytic molecular pathways
The Puerto Rico Alzheimer Disease Initiative (PRADI): A Multisource Ascertainment Approach