Area of research
Genetics · Physiology
Research interest
Research interests include Genetic Associations and Epidemiology, Alzheimer's disease research and treatments, Dementia and Cognitive Impairment Research, and Epigenetics and DNA Methylation.
Multi-ancestry genome-wide meta-analysis of 56,241 individuals identifies known and novel cross-population and ancestry-specific associations as novel risk loci for Alzheimer’s disease
Comparing Alzheimer's genes in African, European, and Amerindian induced pluripotent stem cell–derived microglia
Ancestral genomic functional differences in oligodendroglia: implications for Alzheimer's disease
Country-level incidence of Alzheimer disease and related dementias is associated with increased omega-6-PUFA consumption
Extended genome‐wide association study employing the African genome resources panel identifies novel susceptibility loci for Alzheimer's disease in individuals of African ancestry
Genome-wide association analysis and admixture mapping in a Puerto Rican cohort supports an Alzheimer disease risk locus on chromosome 12
Novel Stop-gain SORL1 Mutation in a Peruvian Family with Alzheimer’s Disease of the PeADI Study (P6-9.017)
African Ancestry Individuals with Higher Educational Attainment Are Resilient to Alzheimer’s Disease Measured by pTau181
Ancestry‐related differences in chromatin accessibility and gene expression of <i>APOE</i> ε4 are associated with Alzheimer's disease risk
A locus at 19q13.31 significantly reduces the ApoE ε4 risk for Alzheimer’s Disease in African Ancestry
Admixture Mapping of Alzheimer’s disease in Caribbean Hispanics identifies a new locus on 22q13.1
Identifying differential regulatory control of <i>APOE</i> ɛ4 on African versus European haplotypes as potential therapeutic targets
Admixture mapping identifies novel Alzheimer's disease risk regions in African Americans
Associations of digital neuro-signatures with molecular and neuroimaging measures of brain resilience: The altoida large cohort study
Using Oligodendrocytes for studies in Alzheimer disease
Increased <i>APOE</i> ε4 expression is associated with the difference in Alzheimer's disease risk from diverse ancestral backgrounds
Dissecting the role of Amerindian genetic ancestry and the ApoE ε4 allele on Alzheimer disease in an admixed Peruvian population
Use of local genetic ancestry to assess <i>TOMM40</i> -523′ and risk for Alzheimer disease
Immune and Inflammatory Pathways Implicated by Whole Blood Transcriptomic Analysis in a Diverse Ancestry Alzheimer’s Disease Cohort
The Puerto Rico Alzheimer Disease Initiative (PRADI): A Multisource Ascertainment Approach
Ancestral origin of ApoE ε4 Alzheimer disease risk in Puerto Rican and African American populations
Rare genetic variation implicated in non-Hispanic white families with Alzheimer disease