Area of research
Physiology · Genetics
Research interest
Research interests include Alzheimer's disease research and treatments, Dementia and Cognitive Impairment Research, Genetic Associations and Epidemiology, and Genomics and Rare Diseases.
Novel early‐onset Alzheimer‐associated genes influence risk through dysregulation of glutamate, immune activation, and intracellular signaling pathways
Alzheimer disease is (sometimes) highly heritable: Drivers of variation in heritability estimates for binary traits, a systematic review
Country-level incidence of Alzheimer disease and related dementias is associated with increased omega-6-PUFA consumption
Extended genome‐wide association study employing the African genome resources panel identifies novel susceptibility loci for Alzheimer's disease in individuals of African ancestry
A global view of the genetic basis of Alzheimer disease
Genetic associations with age at dementia onset in the <i>PSEN1 E280A</i> Colombian kindred
The Early‐Onset Alzheimer's Disease Whole‐Genome Sequencing Project: Study design and methodology
A locus at 19q13.31 significantly reduces the ApoE ε4 risk for Alzheimer’s Disease in African Ancestry
Admixture mapping identifies novel Alzheimer's disease risk regions in African Americans
Early-Onset Alzheimer’s Disease: What Is Missing in Research?
Cross-Species Analyses Identify Dlgap2 as a Regulator of Age-Related Cognitive Decline and Alzheimer’s Dementia
Ancestral origin of ApoE ε4 Alzheimer disease risk in Puerto Rican and African American populations
Genetic Variation in Genes Underlying Diverse Dementias May Explain a Small Proportion of Cases in the Alzheimer’s Disease Sequencing Project
Rare genetic variation implicated in non-Hispanic white families with Alzheimer disease
Linkage analysis of multiplex Caribbean Hispanic families loaded for unexplained early‐onset cases identifies novel Alzheimer's disease loci
Early-Onset Alzheimer Disease and Candidate Risk Genes Involved in Endolysosomal Transport
TREM2 is associated with increased risk for Alzheimer’s disease in African Americans
F‐box/ <scp>LRR</scp> ‐repeat protein 7 is genetically associated with Alzheimer's disease
Global and local ancestry in African‐Americans: Implications for Alzheimer's disease risk
Association of Long Runs of Homozygosity With Alzheimer Disease Among African American Individuals
Linkage analyses in Caribbean Hispanic families identify novel loci associated with familial late‐onset Alzheimer's disease
Variants in the ATP-Binding Cassette Transporter (ABCA7), Apolipoprotein E ϵ4, and the Risk of Late-Onset Alzheimer Disease in African Americans
Independent and epistatic effects of variants in VPS10-d receptors on Alzheimer disease risk and processing of the amyloid precursor protein (APP)