Jianzhong Huo

Area of research

Spectroscopy · Inorganic Chemistry

Research interest

Research topics from publications: Deep learning in two-dimensional materials: Characterization, prediction, and design; Simvastatin inhibits the adipogenesis of bone marrow‑derived mesenchymal stem cells through the downregulation of chemerin/CMKLR1 signaling; Lipid Metabolism, Methylation Aberrant, and Osteoporosis: A Multi-omics Study Based on Mendelian Randomization; Association of ADAMTS4 and ADAMTS5 polymorphisms with musculoskeletal degenerative diseases: a systematic review and meta-analysis; Upper trapezius muscle elasticity in cervical myofascial pain syndrome measured using real-time ultrasound shear-wave elastography; Electroacupuncture promotes functional recovery after spinal cord injury in rats by regulating P2X4R/p38 MAPK signaling pathway and suppressing inflammatory responses. Representative work: Abstract Since the isolation of graphene, two-dimensional (2D) materials have attracted increasing interest because of their excellent chemical and physical properties, as well as promising applications. Nonetheless, particular challenges persist in their further development, particularly in the effective identification of diverse 2D materials, the domains of large-scale and high-precision characterization, also intelligent function prediction and design. These issues are mainly solved by computational techniques, such as density function theory and molecular dynamic simulation, which require powerful computational resources and high time consumption. The booming deep learning methods in rec Simvastatin is effective in the treatment of osteoporosis, partly through the inhibition of the adipogenesis of bone‑marrow derived mesenchymal stem cells (BMSCs). The present study focused on the mechanisms responsible for the inhibitory effects of simvastatin on adipogenesis and examined the effects of simvastatin on the expression of peroxisome proliferator‑activated receptor γ (PPARγ), chemerin, chemokine‑like receptor 1 (CMKLR1), G protein‑coupled receptor 1 (GPR1) and the adipocyte marker gene, adiponectin. BMSCs were isolated from 4‑week‑old female Sprague‑Dawley (SD) rats, and adipogenesis was measured by the absorbance values at 490 nm of Oil Red O dye. The expression of each gene w

Looking for a research collaborator?

Search millions of scientists by field, institution, impact, and funding status — see their work, find their email, and reach out directly.