Area of research
Molecular Medicine · Clinical Biochemistry
Research interest
Research interests include Antibiotic Resistance in Bacteria, Bacterial Identification and Susceptibility Testing, Genomics and Phylogenetic Studies, and Antibiotic Use and Resistance.
Improved Cas9-targeted nanopore sequencing facilitates ultra-deep analysis of genomic variation
An open-source nanopore-only sequencing workflow for analysis of clonal outbreaks delivers short-read level accuracy.
Transcriptional diversification in a human-adapting zoonotic pathogen drives niche-specific evolution.
Efflux pump-mediated resistance to new beta lactam antibiotics in multidrug-resistant gram-negative bacteria.
Bactericidal antibiotic treatment induces damaging inflammation via TLR9 sensing of bacterial DNA.
Regional centromere configuration in the fungal pathogens of the <i>Pneumocystis</i> genus.
Whole-genome sequence of <i>Mucor velutinosus</i> NIH1002, a strain associated with disseminated disease.
Roving methyltransferases generate a mosaic epigenetic landscape and influence evolution in Bacteroides fragilis group.
Comparative Evaluation of Current Biochemical-, Sequencing-, and Proteomic-Based Identification Methods for the Streptococcus bovis Group.
Trimethoprim-Sulfamethoxazole Versus Levofloxacin for <i>Stenotrophomonas maltophilia</i> Infections: A Retrospective Comparative Effectiveness Study of Electronic Health Records from 154 US Hospitals
Hypermutator strains of Pseudomonas aeruginosa reveal novel pathways of resistance to combinations of cephalosporin antibiotics and beta-lactamase inhibitors.
Disseminated <i>Mycoplasma Orale</i> Infection in Patients With Phosphoinositide-3-Kinase Regulatory Subunit 1 Mutations.
Association Between Caseload Surge and COVID-19 Survival in 558 U.S. Hospitals, March to August 2020
In vivo evolution of an emerging zoonotic bacterial pathogen in an immunocompromised human host.
Manual Reading of Sensititre Broth Microdilution System Panels Improves Accuracy of Susceptibility Reporting for Polymyxin Antibiotics
Prevalence of Antibiotic-Resistant Pathogens in Culture-Proven Sepsis and Outcomes Associated With Inadequate and Broad-Spectrum Empiric Antibiotic Use
Inappropriate empirical antibiotic therapy for bloodstream infections based on discordant in-vitro susceptibilities: a retrospective cohort analysis of prevalence, predictors, and mortality risk in US hospitals
Effectiveness of adjunctive clindamycin in β-lactam antibiotic-treated patients with invasive β-haemolytic streptococcal infections in US hospitals: a retrospective multicentre cohort study
A Phylogeny-Informed Proteomics Approach for Species Identification within the Burkholderia cepacia Complex.
Difficult-to-Treat Resistance in Gram-negative Bacteremia at 173 US Hospitals: Retrospective Cohort Analysis of Prevalence, Predictors, and Outcome of Resistance to All First-line Agents
Severe BCG-osis Misdiagnosed as Multidrug-Resistant Tuberculosis in an IL-12Rβ1-Deficient Peruvian Girl
Multi-institute analysis of carbapenem resistance reveals remarkable diversity, unexplained mechanisms, and limited clonal outbreaks