Area of research
Epidemiology · Immunology
Research interest
Research interests include Sepsis Diagnosis and Treatment, Immune Response and Inflammation, Nitric Oxide and Endothelin Effects, and Antibiotic Use and Resistance.
Myocyte Damage and Mass Loss Drives Increasing Water Content, Compliance, and Survival in Septic Cardiomyopathy
BMPR2 Loss Activates AKT by Disrupting DLL4/NOTCH1 and PPARγ Signaling in Pulmonary Arterial Hypertension.
Risks of Restrictive Versus Liberal Red Blood Cell Transfusion Strategies in Patients With Cardiovascular Disease: An Updated Meta-Analysis.
Cardiac Magnetic Resonance Studies in a Large Animal Model That Simulates the Cardiac Abnormalities of Human Septic Shock.
Endothelial PHD2 deficiency induces apoptosis resistance and inflammation via AKT activation and AIP1 loss independent of HIF2α.
In a Canine Model of Septic Shock, Cardiomyopathy Occurs Independent of Catecholamine Surges and Cardiac Microvascular Ischemia.
Reliability of Admission Procalcitonin Testing for Capturing Bacteremia Across the Sepsis Spectrum: Real-World Utilization and Performance Characteristics, 65 U.S. Hospitals, 2008–2017*
Inflammation and DKK1-induced AKT activation contribute to endothelial dysfunction following NR2F2 loss.
Trimethoprim-Sulfamethoxazole Versus Levofloxacin for <i>Stenotrophomonas maltophilia</i> Infections: A Retrospective Comparative Effectiveness Study of Electronic Health Records from 154 US Hospitals
Mineralocorticoid receptor antagonist treatment of established pulmonary arterial hypertension improves interventricular dependence in the SU5416-hypoxia rat model.
Association Between Caseload Surge and COVID-19 Survival in 558 U.S. Hospitals, March to August 2020
Association Between Caseload Surge and COVID-19 Survival in 558 U.S. Hospitals, March to August 2020.
Type I interferon activation and endothelial dysfunction in caveolin-1 insufficiency-associated pulmonary arterial hypertension.
Mechanistic insights into cell-free hemoglobin-induced injury during septic shock.
Prevalence of Antibiotic-Resistant Pathogens in Culture-Proven Sepsis and Outcomes Associated With Inadequate and Broad-Spectrum Empiric Antibiotic Use
Inappropriate empirical antibiotic therapy for bloodstream infections based on discordant in-vitro susceptibilities: a retrospective cohort analysis of prevalence, predictors, and mortality risk in US hospitals
Effectiveness of adjunctive clindamycin in β-lactam antibiotic-treated patients with invasive β-haemolytic streptococcal infections in US hospitals: a retrospective multicentre cohort study
Difficult-to-Treat Resistance in Gram-negative Bacteremia at 173 US Hospitals: Retrospective Cohort Analysis of Prevalence, Predictors, and Outcome of Resistance to All First-line Agents
Incidence and Trends of Sepsis in US Hospitals Using Clinical vs Claims Data, 2009-2014
Estimating Ten-Year Trends in Septic Shock Incidence and Mortality in United States Academic Medical Centers Using Clinical Data
Hypothalamic-pituitary-adrenal axis in lethal canine <i>Staphylococcus aureus</i> pneumonia
Beneficial effects of stress-dose corticosteroid therapy in canines depend on the severity of staphylococcal pneumonia