Area of research
Cellular and Molecular Neuroscience · Cognitive Neuroscience
Research interest
Research interests include Neuroscience and Neuropharmacology Research, Memory and Neural Mechanisms, Alzheimer's disease research and treatments, and Stress Responses and Cortisol.
Inhibition of an Alzheimer’s disease–associated form of necroptosis rescues neuronal death in mouse models
Molecular and cognitive signatures of ageing partially restored through synthetic delivery of IL2 to the brain
Astrocyte-targeted gene delivery of interleukin 2 specifically increases brain-resident regulatory T cell numbers and protects against pathological neuroinflammation
Astrocyte calcium dysfunction causes early network hyperactivity in Alzheimer’s disease
AAV‐mediated delivery of an anti‐BACE1 VHH alleviates pathology in an Alzheimer's disease model
Restoring miR-132 expression rescues adult hippocampal neurogenesis and memory deficits in Alzheimer’s disease
Lowering Synaptogyrin-3 expression rescues Tau-induced memory defects and synaptic loss in the presence of microglial activation
Microglia Require CD4 T Cells to Complete the Fetal-to-Adult Transition
The autism- and schizophrenia-associated protein CYFIP1 regulates bilateral brain connectivity and behaviour
EphA4 loss improves social memory performance and alters dendritic spine morphology without changes in amyloid pathology in a mouse model of Alzheimer’s disease
A20 critically controls microglia activation and inhibits inflammasome-dependent neuroinflammation
Deregulation of neuronal miRNAs induced by amyloid-β or TAU pathology
High fat diet treatment impairs hippocampal long-term potentiation without alterations of the core neuropathological features of Alzheimer disease
Quinolinic acid injection in mouse medial prefrontal cortex affects reversal learning abilities, cortical connectivity and hippocampal synaptic plasticity
Loss of GPR3 reduces the amyloid plaque burden and improves memory in Alzheimer’s disease mouse models
Dysregulated ADAM10-Mediated Processing of APP during a Critical Time Window Leads to Synaptic Deficits in Fragile X Syndrome
Deficiency of the miR-29a/b-1 cluster leads to ataxic features and cerebellar alterations in mice
SSP-002392, a new 5-HT4 receptor agonist, dose-dependently reverses scopolamine-induced learning and memory impairments in C57Bl/6 mice
Low hippocampal PI(4,5)P2 contributes to reduced cognition in old mice as a result of loss of MARCKS
TUDCA, a Bile Acid, Attenuates Amyloid Precursor Protein Processing and Amyloid-β Deposition in APP/PS1 Mice
Tauroursodeoxycholic acid (TUDCA) supplementation prevents cognitive impairment and amyloid deposition in APP/PS1 mice
<scp>LPA</scp><sub>5</sub> receptor plays a role in pain sensitivity, emotional exploration and reversal learning