Area of research
Cardiology and Cardiovascular Medicine · Molecular Biology
Research interest
Research interests include Hypertrophic cardiomyopathy, Internal medicine, Medicine, Cardiology, Sarcomere, and Myofibril.
Optogenetic manipulation of cardiac electrical dynamics using sub-threshold illumination: dissecting the role of cardiac alternans in terminating rapid rhythms
Genotype-Driven Pathogenesis of Atrial Fibrillation in Hypertrophic Cardiomyopathy: The Case of Different TNNT2 Mutations
Mutation location of HCM-causing troponin T mutations defines the degree of myofilament dysfunction in human cardiomyocytes
Electrophysiological and Contractile Effects of Disopyramide in Patients With Obstructive Hypertrophic Cardiomyopathy
Myocardial overexpression of ANKRD1 causes sinus venosus defects and progressive diastolic dysfunction
Defining the diagnostic effectiveness of genes for inclusion in panels: the experience of two decades of genetic testing for hypertrophic cardiomyopathy at a single center
Real‐time optical manipulation of cardiac conduction in intact hearts
Ranolazine Prevents Phenotype Development in a Mouse Model of Hypertrophic Cardiomyopathy
Pathogenesis of Hypertrophic Cardiomyopathy is Mutation Rather Than Disease Specific: A Comparison of the Cardiac Troponin T E163R and R92Q Mouse Models
Targets for therapy in sarcomeric cardiomyopathies
Novel insights on the relationship between T-tubular defects and contractile dysfunction in a mouse model of hypertrophic cardiomyopathy
Clinical Phenotype and Outcome of Hypertrophic Cardiomyopathy Associated With Thin-Filament Gene Mutations
Gene-specific increase in the energetic cost of contraction in hypertrophic cardiomyopathy caused by thick filament mutations
Faster cross‐bridge detachment and increased tension cost in human hypertrophic cardiomyopathy with the R403Q <i>MYH7</i> mutation
Mutations in MYH7 reduce the force generating capacity of sarcomeres in human familial hypertrophic cardiomyopathy
Deleting exon 55 from the nebulin gene induces severe muscle weakness in a mouse model for nemaline myopathy
Tropomyosin Ser-283 pseudo-phosphorylation slows myofibril relaxation