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Siegfried S. F. Leung

Sunesis (United States) · US

Area of research

Molecular Biology · Oncology

Research interest

Research interests include Chemical Synthesis and Analysis, Cancer-related Molecular Pathways, Trypanosoma species research and implications, and Click Chemistry and Applications.

h-index

15

citations

1,832

works

23

NIH funding

—

primary concept

—

email

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Recent publications

Discovery of Potent and Orally Bioavailable Macrocyclic Peptide–Peptoid Hybrid CXCR7 Modulators

Journal of Medicinal Chemistry 2017cited by 70position: middledoi

Simple Predictive Models of Passive Membrane Permeability Incorporating Size-Dependent Membrane-Water Partition

Journal of Chemical Information and Modeling 2016cited by 65position: firstdoi

Peptide to Peptoid Substitutions Increase Cell Permeability in Cyclic Hexapeptides

Organic Letters 2015cited by 84position: middledoi

Cell-Permeable Cyclic Peptides from Synthetic Libraries Inspired by Natural Products

Journal of the American Chemical Society 2014cited by 211position: middledoi

Optimizing PK properties of cyclic peptides: the effect of side chain substitutions on permeability and clearance

MedChemComm 2012cited by 131position: middledoi

Testing Physical Models of Passive Membrane Permeation

Journal of Chemical Information and Modeling 2012cited by 122position: firstdoi

Grants

No grants ingested yet.

Frequent collaborators

Matthew P. Jacobson · Sunesis (United States)5 papers (2012–2016)R. Scott Lokey · University of California System3 papers (2012–2015)Alexandra R. Ponkey · University of California, Santa Cruz2 papers (2014–2015)— · 2 papers (2012–2015)— · 2 papers (2012–2015)Amit S. Kalgutkar · Pfizer (United States)2 papers (2012–2015)— · 2 papers (2012–2015)— · 2 papers (2012–2015)— · 2 papers (2012–2015)Heather Eng · PRX Research2 papers (2012–2015)William M. Hewitt · Center for Cancer Research1 papers (2014–2014)Kelsie M. Rodriguez · University of California, Santa Cruz1 papers (2015–2015)Arthur C Rand · University of California, Santa Cruz1 papers (2012–2012)Raman Sharma · Dartmouth College1 papers (2012–2012)Joshua Schwochert · University of California, Santa Cruz1 papers (2015–2015)— · 1 papers (2014–2014)Melissa Thang · University of California, Santa Cruz1 papers (2015–2015)Rushia Turner · University of California, Santa Cruz1 papers (2015–2015)Jona Mijalkovic · Erasmus University Rotterdam1 papers (2012–2012)Yizhong Zhang · National University of Singapore1 papers (2012–2012)