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R. Scott Lokey

University of California System · US
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Area of research
Molecular Biology · Pharmacology
Research interest
Research interests include Chemistry, Cyclic peptide, Peptide, Bioavailability, Peptoid, and Membrane permeability.
h-index
citations
1,417
works
8
NIH funding
primary concept
email

Recent publications

Drug‐Like Properties in Macrocycles above MW 1000: Backbone Rigidity versus Side‐Chain Lipophilicity
Angewandte Chemie International Edition 2020cited by 73position: lastdoi
Retrospective analysis of natural products provides insights for future discovery trends
Proceedings of the National Academy of Sciences 2017cited by 537position: middledoi
Discovery of Potent and Orally Bioavailable Macrocyclic Peptide–Peptoid Hybrid CXCR7 Modulators
Journal of Medicinal Chemistry 2017cited by 70position: middledoi
Beyond Cyclosporine A: Conformation-Dependent Passive Membrane Permeabilities of Cyclic Peptide Natural Products
Future Medicinal Chemistry 2015cited by 175position: lastdoi
Probing the Physicochemical Boundaries of Cell Permeability and Oral Bioavailability in Lipophilic Macrocycles Inspired by Natural Products
Journal of Medicinal Chemistry 2015cited by 136position: lastdoi
Peptide to Peptoid Substitutions Increase Cell Permeability in Cyclic Hexapeptides
Organic Letters 2015cited by 84position: lastdoi
Cell-Permeable Cyclic Peptides from Synthetic Libraries Inspired by Natural Products
Journal of the American Chemical Society 2014cited by 211position: lastdoi
Optimizing PK properties of cyclic peptides: the effect of side chain substitutions on permeability and clearance
MedChemComm 2012cited by 131position: lastdoi

Grants

No grants ingested yet.

Frequent collaborators

Matthew P. Jacobson · Sunesis (United States)5 papers (2012–2015)Cameron R. Pye · University of California, Santa Cruz4 papers (2014–2020)Joshua Schwochert · University of California, Santa Cruz3 papers (2015–2020) · 3 papers (2012–2015) · 3 papers (2012–2015)Amit S. Kalgutkar · Pfizer (United States)3 papers (2012–2015) · 3 papers (2012–2015)Siegfried S. F. Leung · Sunesis (United States)3 papers (2012–2015)William M. Hewitt · Center for Cancer Research2 papers (2014–2015)Alexandra R. Ponkey · University of California, Santa Cruz2 papers (2014–2015)Andrew T. Bockus · University of California, Santa Cruz2 papers (2015–2015)Katrina W. Lexa · Tetra Therapeutics (United States)2 papers (2015–2015) · 2 papers (2012–2015) · 2 papers (2012–2015)Heather Eng · PRX Research2 papers (2012–2015)Phillip Crews · University of California System1 papers (2015–2015)Christopher Ahlbach · University of San Francisco1 papers (2015–2015)Kelsie M. Rodriguez · University of California, Santa Cruz1 papers (2015–2015)Arthur C Rand · University of California, Santa Cruz1 papers (2012–2012)Raman Sharma · Dartmouth College1 papers (2012–2012)
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