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Katrina W. Lexa

Tetra Therapeutics (United States) · US
Area of research
Molecular Biology · Computational Theory and Mathematics
Research interest
Research interests include Protein Structure and Dynamics, Computational Drug Discovery Methods, Chemical Synthesis and Analysis, and HIV/AIDS drug development and treatment.
h-index
25
citations
2,102
works
42
NIH funding
primary concept
email

Recent publications

CD98hc is a target for brain delivery of biotherapeutics
Nature Communications 2023cited by 83position: middledoi
Rescue of a lysosomal storage disorder caused by Grn loss of function with a brain penetrant progranulin biologic
Cell 2021cited by 224position: middledoi
Ticks Resist Skin Commensals with Immune Factor of Bacterial Origin
Cell 2020cited by 62position: middledoi
Combining traditional 2D and modern physical organic-derived descriptors to predict enhanced enantioselectivity for the key aza-Michael conjugate addition in the synthesis of Prevymis™ (letermovir)
Chemical Science 2018cited by 29position: middledoi
Exhaustive Conformational Sampling of Complex Fused Ring Macrocycles Using Inverse Kinematics
Journal of Chemical Theory and Computation 2016cited by 66position: middledoi
Beyond Cyclosporine A: Conformation-Dependent Passive Membrane Permeabilities of Cyclic Peptide Natural Products
Future Medicinal Chemistry 2015cited by 175position: middledoi
Probing the Physicochemical Boundaries of Cell Permeability and Oral Bioavailability in Lipophilic Macrocycles Inspired by Natural Products
Journal of Medicinal Chemistry 2015cited by 136position: middledoi
De novo mutations in KIF1A cause progressive encephalopathy and brain atrophy
Annals of Clinical and Translational Neurology 2015cited by 123position: middledoi
A Structure-Based Model for Predicting Serum Albumin Binding
PLoS ONE 2014cited by 78position: firstdoi
Structure of a Peptidoglycan Amidase Effector Targeted to Gram-Negative Bacteria by the Type VI Secretion System
Cell Reports 2012cited by 108position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Matthew P. Jacobson · Sunesis (United States)4 papers (2014–2016)Seemay Chou · Arcadia2 papers (2012–2020)R. Scott Lokey · University of California System2 papers (2015–2015)Andrew T. Bockus · University of California, Santa Cruz2 papers (2015–2015)Waldemar Vollmer · University of Queensland2 papers (2012–2020)Amit S. Kalgutkar · Pfizer (United States)1 papers (2015–2015) · 1 papers (2015–2015)Zhijian Liu · Southwest University1 papers (2018–2018)Valerie Chen · University of California, Santa Cruz1 papers (2015–2015) · 1 papers (2015–2015)Nizar Smaoui · AbbVie (United States)1 papers (2015–2015)Ronald D. Vale · University of California, San Francisco1 papers (2015–2015)Maura R.Z. Madou · University of California, San Francisco1 papers (2015–2015)Nhat Khai Bui · Newcastle University1 papers (2012–2012)Thomas Andrew Burrow · Ludwig-Maximilians-Universität München1 papers (2015–2015) · 1 papers (2015–2015) · 1 papers (2018–2018)Fauna Yarza · Io Therapeutics (United States)1 papers (2020–2020) · 1 papers (2015–2015) · 1 papers (2018–2018)