Area of research
Neurology · Biological Psychiatry
Research interest
Research interests include Neuroinflammation and Neurodegeneration Mechanisms, Tryptophan and brain disorders, Stress Responses and Cortisol, and Neurogenesis and neuroplasticity mechanisms.
Long-read RNA sequencing atlas of human microglia isoforms elucidates disease-associated genetic regulation of splicing
Integrated Stress Response Signatures Drive Monocyte Dysfunction in <i>GBA1</i> - and <i>LRRK2</i> -Linked Parkinson’s Disease
A microglia-containing cerebral organoid model to study early life immune challenges
TYROBP/DAP12 knockout in Huntington’s disease Q175 mice cell-autonomously decreases microglial expression of disease-associated genes and non-cell-autonomously mitigates astrogliosis and motor deterioration
Microglia undergo molecular and functional adaptations to dark and light phases in male laboratory mice
A microglia-containing cerebral organoid model to study early life immune challenges
Long-read RNA-seq atlas of novel microglia isoforms elucidates disease-associated genetic regulation of splicing
Deletion of the microglial transmembrane immune signaling adaptor TYROBP ameliorates Huntington’s disease mouse phenotype
A CRISPR-Cas9–engineered mouse model for GPI-anchor deficiency mirrors human phenotypes and exhibits hippocampal synaptic dysfunctions
Maternal immune activation results in complex microglial transcriptome signature in the adult offspring that is reversed by minocycline treatment
Ly6Chi Monocytes Provide a Link between Antibiotic-Induced Changes in Gut Microbiota and Adult Hippocampal Neurogenesis