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Helmut Kettenmann

Shenzhen University · CN
Area of research
Neurology · Cellular and Molecular Neuroscience
Research interest
Research interests include Microglia, Biology, Neuroscience, Glioma, Cell biology, and Astrocyte.
h-index
citations
7,791
works
38
NIH funding
primary concept
email

Recent publications

Peripheral nervous system microglia-like cells regulate neuronal soma size throughout evolution
Cell 2025cited by 32position: middledoi
Multicolor fate mapping of microglia reveals polyclonal proliferation, heterogeneity, and cell-cell interactions after ischemic stroke in mice
Nature Communications 2025cited by 2position: middledoi
Extracellular microRNAs modulate human microglial function through TLR8
Frontiers in Immunology 2025cited by 1position: middledoi
Microglia undergo molecular and functional adaptations to dark and light phases in male laboratory mice
Brain Behavior and Immunity 2024cited by 16position: middledoi
Alzheimer's Disease Risk Gene <i>SORL1</i> Promotes Receptiveness of Human Microglia to Pro‐Inflammatory Stimuli
Glia 2024cited by 12position: middledoi
The IgCAM BT-IgSF (IgSF11) Is Essential for Connexin43-Mediated Astrocyte–Astrocyte Coupling in Mice
eNeuro 2024cited by 7position: middledoi
Sex-specific microglia state in the Neuroligin-4 knock-out mouse model of autism spectrum disorder
Brain Behavior and Immunity 2023cited by 44position: middledoi
Distinct SARS-CoV-2 RNA fragments activate Toll-like receptors 7 and 8 and induce cytokine release from human macrophages and microglia
Frontiers in Immunology 2023cited by 31position: middledoi
Small molecule inhibiting microglial nitric oxide release could become a potential treatment for neuroinflammation
PLoS ONE 2023cited by 11position: middledoi
Neurofibromin 1 mutations impair the function of human induced pluripotent stem cell-derived microglia
Disease Models & Mechanisms 2023cited by 5position: lastdoi
Microglia states and nomenclature: A field at its crossroads
Neuron 2022cited by 1,824position: middledoi
A single‐cell RNA labeling strategy for measuring stress response upon tissue dissociation
Molecular Systems Biology 2022cited by 26position: middledoi
The IgCAM BT-IgSF (IgSF11) is essential for connexin43-mediated astrocyte-astrocyte and ependymal cell-cell coupling in mice
bioRxiv (Cold Spring Harbor Laboratory) 2022cited by 2position: middledoi
Reactive astrocyte nomenclature, definitions, and future directions
Nature Neuroscience 2021cited by 2,312position: middledoi
Glial cell line‐derived neurotrophic factor increases matrix metallopeptidase 9 and 14 expression in microglia and promotes microglia‐mediated glioma progression
Journal of Neuroscience Research 2021cited by 27position: lastdoi
UNC93B1 Is Widely Expressed in the Murine CNS and Is Required for Neuroinflammation and Neuronal Injury Induced by MicroRNA let-7b
Frontiers in Immunology 2021cited by 5position: middledoi
Synergistic Toll-like Receptor 3/9 Signaling Affects Properties and Impairs Glioma-Promoting Activity of Microglia
Journal of Neuroscience 2020cited by 57position: lastdoi
Activation of Toll-like receptor 5 in microglia modulates their function and triggers neuronal injury
Acta Neuropathologica Communications 2020cited by 43position: middledoi
Correction to: Comprehensive gene expression meta-analysis identifies signature genes that distinguish microglia from peripheral monocytes/macrophages in health and glioma
Acta Neuropathologica Communications 2020cited by 30position: middledoi
Deletion of muscarinic acetylcholine receptor 3 in microglia impacts brain ischemic injury
Brain Behavior and Immunity 2020cited by 26position: lastdoi
Neurofibromatosis 1 - Mutant microglia exhibit sexually-dimorphic cyclic AMP-dependent purinergic defects
Neurobiology of Disease 2020cited by 17position: middledoi
Down-regulation of Aquaporin-1 mediates a microglial phenotype switch affecting glioma growth
Experimental Cell Research 2020cited by 12position: middledoi
Comprehensive gene expression meta-analysis identifies signature genes that distinguish microglia from peripheral monocytes/macrophages in health and glioma
Acta Neuropathologica Communications 2019cited by 175position: middledoi
Human Mesenchymal glioblastomas are characterized by an increased immune cell presence compared to Proneural and Classical tumors
OncoImmunology 2019cited by 163position: middledoi
let-7 MicroRNAs Regulate Microglial Function and Suppress Glioma Growth through Toll-Like Receptor 7
Cell Reports 2019cited by 114position: middledoi
Oligodendrocytes in the Mouse Corpus Callosum Maintain Axonal Function by Delivery of Glucose
Cell Reports 2018cited by 145position: lastdoi
Maternal immune activation results in complex microglial transcriptome signature in the adult offspring that is reversed by minocycline treatment
Translational Psychiatry 2017cited by 218position: middledoi
Distinguishing features of microglia- and monocyte-derived macrophages after stroke
Acta Neuropathologica 2017cited by 114position: middledoi
Loss of host-derived osteopontin creates a glioblastoma-promoting microenvironment
Neuro-Oncology 2017cited by 42position: lastdoi
Astrocytic Calcium Waves Signal Brain Injury to Neural Stem and Progenitor Cells
Stem Cell Reports 2017cited by 22position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Marcus Semtner · Max Delbrück Center9 papers (2018–2025)Susanne A. Wolf · Helmholtz Association of German Research Centres9 papers (2013–2025)Alice Buonfiglioli · Allen Institute for Brain Science6 papers (2017–2021)David H. Gutmann · Lantmännen6 papers (2015–2023)Seija Lehnardt · Humboldt-Universität zu Berlin6 papers (2019–2025)Christina Krüger · Humboldt-Universität zu Berlin5 papers (2019–2025)Verena Haage · University of California, Berkeley5 papers (2019–2021)Dolores Hambardzumyan · Cancer Institute (WIA)5 papers (2015–2020)Omar Dzaye · Memorial Sloan Kettering Cancer Center5 papers (2019–2021)Yimin Huang · Case Western Reserve University4 papers (2019–2021)Matthias Endres · Excellence Cluster Universe4 papers (2013–2025)Niklas Meyer · University of Oslo4 papers (2018–2024)Michael Synowitz · Huazhong University of Science and Technology4 papers (2012–2020)Edyta Motta · Helmholtz Association of German Research Centres4 papers (2020–2025)Dilansu Güneykaya · Max Delbrück Center4 papers (2017–2023)Philipp Jordan · Max Delbrück Center4 papers (2017–2023)Ibrahim E. Efe · Max Delbrück Center4 papers (2019–2023)Karen Gertz · Humboldt-Universität zu Berlin3 papers (2017–2025)Zhihong Chen · Chinese Academy of Medical Sciences & Peking Union Medical College3 papers (2019–2020)Feng Hu · Nanchang University3 papers (2020–2021)