Area of research
Immunology · Neurology
Research interest
Research interests include Neuroinflammation and Neurodegeneration Mechanisms, Immune Response and Inflammation, MicroRNA in disease regulation, and Immune cells in cancer.
Microglia-Derived Extracellular Vesicles from Alzheimer’s Disease Patients Carry miRNAs Driving a Neuroinflammatory Response
Activation of intestinal endogenous retroviruses by alcohol exacerbates liver disease
Neurodegenerative disease-associated microRNAs acting as signaling molecules modulate CNS neuron structure and viability
Extracellular microRNAs modulate human microglial function through TLR8
miR-154-5p Is a Novel Endogenous Ligand for TLR7 Inducing Microglial Activation and Neuronal Injury
Distinct SARS-CoV-2 RNA fragments activate Toll-like receptors 7 and 8 and induce cytokine release from human macrophages and microglia
MicroRNA-100-5p and microRNA-298-5p released from apoptotic cortical neurons are endogenous Toll-like receptor 7/8 ligands that contribute to neurodegeneration
Novel protocol for the isolation of highly purified neonatal murine microglia and astrocytes
Structure-aware machine learning identifies microRNAs operating as Toll-like receptor 7/8 ligands
UNC93B1 Is Widely Expressed in the Murine CNS and Is Required for Neuroinflammation and Neuronal Injury Induced by MicroRNA let-7b
Human endogenous retrovirus HERV-K(HML-2) RNA causes neurodegeneration through Toll-like receptors
Synergistic Toll-like Receptor 3/9 Signaling Affects Properties and Impairs Glioma-Promoting Activity of Microglia
Activation of Toll-like receptor 5 in microglia modulates their function and triggers neuronal injury
Identification of CNS Injury-Related microRNAs as Novel Toll-Like Receptor 7/8 Signaling Activators by Small RNA Sequencing
Abnormal brain structure and behavior in MyD88-deficient mice
let-7 MicroRNAs Regulate Microglial Function and Suppress Glioma Growth through Toll-Like Receptor 7
An unconventional role for miRNA: let-7 activates Toll-like receptor 7 and causes neurodegeneration
Expression of Toll-Like Receptors in the Developing Brain
Elevation in Type I Interferons Inhibits HCN1 and Slows Cortical Neuronal Oscillations