Area of research
Molecular Biology · Cancer Research
Research interest
Research interests include Cancer, Hypoxia, and Metabolism, Angiogenesis and VEGF in Cancer, Pluripotent Stem Cells Research, and Single-cell and spatial transcriptomics.
VEGF-B prevents excessive angiogenesis by inhibiting FGF2/FGFR1 pathway
Single cell atlas identifies lipid-processing and immunomodulatory endothelial cells in healthy and malignant breast
The pulmonary vasculature in lethal COVID-19 and idiopathic pulmonary fibrosis at single-cell resolution
Tumor vessel co-option probed by single-cell analysis
Protocols for endothelial cell isolation from mouse tissues: brain, choroid, lung, and muscle
Protocols for endothelial cell isolation from mouse tissues: kidney, spleen, and testis
Single-Cell Transcriptome Atlas of Murine Endothelial Cells
An Integrated Gene Expression Landscape Profiling Approach to Identify Lung Tumor Endothelial Cell Heterogeneity and Angiogenic Candidates
Single-Cell RNA Sequencing Maps Endothelial Metabolic Plasticity in Pathological Angiogenesis
DNA methylation repels binding of hypoxia-inducible transcription factors to maintain tumor immunotolerance
c-Rel orchestrates energy-dependent epithelial and macrophage reprogramming in fibrosis
Single-Cell RNA Sequencing Reveals Renal Endothelium Heterogeneity and Metabolic Adaptation to Water Deprivation
Leigh Syndrome Mouse Model Can Be Rescued by Interventions that Normalize Brain Hyperoxia, but Not HIF Activation
Impairment of Angiogenesis by Fatty Acid Synthase Inhibition Involves mTOR Malonylation
Role of glutamine synthetase in angiogenesis beyond glutamine synthesis
Serine Synthesis via PHGDH Is Essential for Heme Production in Endothelial Cells
EndoDB: a database of endothelial cell transcriptomics data
Role of glutamine and interlinked asparagine metabolism in vessel formation
Tumour hypoxia causes DNA hypermethylation by reducing TET activity
Inhibition of the Glycolytic Activator PFKFB3 in Endothelium Induces Tumor Vessel Normalization, Impairs Metastasis, and Improves Chemotherapy
The role of fatty acid β-oxidation in lymphangiogenesis
Deletion or Inhibition of the Oxygen Sensor PHD1 Protects against Ischemic Stroke via Reprogramming of Neuronal Metabolism
Fatty acid carbon is essential for dNTP synthesis in endothelial cells
Role of PFKFB3-Driven Glycolysis in Vessel Sprouting
Sustained function of alginate-encapsulated human islet cell implants in the peritoneal cavity of mice leading to a pilot study in a type 1 diabetic patient
Incomplete and transitory decrease of glycolysis