Area of research
Cancer Research · Molecular Biology
Research interest
Research interests include Cancer, Hypoxia, and Metabolism, Angiogenesis and VEGF in Cancer, Immune cells in cancer, and Single-cell and spatial transcriptomics.
Nucleotide metabolism in cancer cells fuels a UDP-driven macrophage cross-talk, promoting immunosuppression and immunotherapy resistance
Integrated single-cell RNA-seq analysis reveals mitochondrial calcium signaling as a modulator of endothelial-to-mesenchymal transition
FOXF1 promotes tumor vessel normalization and prevents lung cancer progression through FZD4
Mitochondrial respiration supports autophagy to provide stress resistance during quiescence
Identification of vascular cues contributing to cancer cell stemness and function
Protocols for endothelial cell isolation from mouse tissues: brain, choroid, lung, and muscle
Protocols for endothelial cell isolation from mouse tissues: kidney, spleen, and testis
Single-Cell Transcriptome Atlas of Murine Endothelial Cells
An Integrated Gene Expression Landscape Profiling Approach to Identify Lung Tumor Endothelial Cell Heterogeneity and Angiogenic Candidates
Single-Cell RNA Sequencing Maps Endothelial Metabolic Plasticity in Pathological Angiogenesis
Single-Cell RNA Sequencing Reveals Renal Endothelium Heterogeneity and Metabolic Adaptation to Water Deprivation
Quiescent Endothelial Cells Upregulate Fatty Acid β-Oxidation for Vasculoprotection via Redox Homeostasis
Impairment of Angiogenesis by Fatty Acid Synthase Inhibition Involves mTOR Malonylation
Role of glutamine synthetase in angiogenesis beyond glutamine synthesis
Serine Synthesis via PHGDH Is Essential for Heme Production in Endothelial Cells
EndoDB: a database of endothelial cell transcriptomics data
Role of glutamine and interlinked asparagine metabolism in vessel formation
Hypoxia determines survival outcomes of bacterial infection through HIF-1α–dependent reprogramming of leukocyte metabolism
Inhibition of the Glycolytic Activator PFKFB3 in Endothelium Induces Tumor Vessel Normalization, Impairs Metastasis, and Improves Chemotherapy
Macrophage Metabolism Controls Tumor Blood Vessel Morphogenesis and Metastasis
The role of fatty acid β-oxidation in lymphangiogenesis
Dual inhibition of Ang-2 and VEGF receptors normalizes tumor vasculature and prolongs survival in glioblastoma by altering macrophages
HIF-1α Promotes Glutamine-Mediated Redox Homeostasis and Glycogen-Dependent Bioenergetics to Support Postimplantation Bone Cell Survival
Meta‐analysis of clinical metabolic profiling studies in cancer: challenges and opportunities
Adequate hypoxia inducible factor 1α signaling is indispensable for bone regeneration
Fatty acid carbon is essential for dNTP synthesis in endothelial cells
Principles of targeting endothelial cell metabolism to treat angiogenesis and endothelial cell dysfunction in disease
The multifaceted activity of VEGF in angiogenesis – Implications for therapy responses
Partial and Transient Reduction of Glycolysis by PFKFB3 Blockade Reduces Pathological Angiogenesis