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Toshinari Yamashita

Showa University Hospital · JP
Area of research
Oncology · Pulmonary and Respiratory Medicine
Research interest
Research interests include Advanced Breast Cancer Therapies, HER2/EGFR in Cancer Research, Breast Cancer Treatment Studies, and Cancer Treatment and Pharmacology.
h-index
32
citations
11,256
works
267
NIH funding
primary concept
Medicine
email

Recent publications

Trastuzumab Deruxtecan plus Pertuzumab for HER2-Positive Metastatic Breast Cancer
New England Journal of Medicine 2025cited by 30position: middledoi
Trastuzumab deruxtecan (T-DXd) + pertuzumab (P) vs taxane + trastuzumab + pertuzumab (THP) for first-line (1L) treatment of patients (pts) with human epidermal growth factor receptor 2–positive (HER2+) advanced/metastatic breast cancer (a/mBC): Interim results from DESTINY-Breast09.
Journal of Clinical Oncology 2025cited by 27position: middledoi
First-in-Human Phase I/IIa Study of the First-in-Class CDK2/4/6 Inhibitor PF-06873600 Alone or with Endocrine Therapy in Patients with Breast Cancer
Clinical Cancer Research 2025cited by 12position: middledoi
Inhibition of lysine acetyltransferase KAT6 in ER+HER2− metastatic breast cancer: a phase 1 trial
Nature Medicine 2024cited by 50position: middledoi
377O A pooled analysis of trastuzumab deruxtecan (T-DXd) in patients (pts) with HER2-positive (HER2+) metastatic breast cancer (mBC) with brain metastases (BMs) from DESTINY-Breast (DB) -01, -02, and -03
Annals of Oncology 2023cited by 56position: middledoi
FXYD3 functionally demarcates an ancestral breast cancer stem cell subpopulation with features of drug-tolerant persisters
Journal of Clinical Investigation 2023cited by 29position: middledoi
Trastuzumab Deruxtecan in Previously Treated HER2-Low Advanced Breast Cancer
New England Journal of Medicine 2022cited by 2,483position: middledoi
Adjuvant abemaciclib combined with endocrine therapy for high-risk early breast cancer: safety and patient-reported outcomes from the monarchE study
Annals of Oncology 2022cited by 122position: middledoi
Abstract PD3-06: Updated results from DESTINY-breast01, a phase 2 trial of trastuzumab deruxtecan (T-DXd ) in HER2 positive metastatic breast cancer
Cancer Research 2021cited by 62position: middledoi
Trastuzumab deruxtecan (T-DXd) in patients with HER2+ metastatic breast cancer with brain metastases: A subgroup analysis of the DESTINY-Breast01 trial.
Journal of Clinical Oncology 2021cited by 52position: middledoi
Alpelisib plus fulvestrant for PIK3CA-mutated, hormone receptor-positive, human epidermal growth factor receptor-2–negative advanced breast cancer: final overall survival results from SOLAR-1
Annals of Oncology 2020cited by 594position: middledoi
Time course and management of key adverse events during the randomized phase III SOLAR-1 study of PI3K inhibitor alpelisib plus fulvestrant in patients with HR-positive advanced breast cancer
Annals of Oncology 2020cited by 185position: middledoi
LBA18 Overall survival (os) results from SOLAR-1, a phase III study of alpelisib (ALP) + fulvestrant (FUL) for hormone receptor-positive (HR+), human epidermal growth factor receptor 2-negative (HER2–) advanced breast cancer (ABC)
Annals of Oncology 2020cited by 20position: middledoi
Alpelisib for <i>PIK3CA</i> -Mutated, Hormone Receptor–Positive Advanced Breast Cancer
New England Journal of Medicine 2019cited by 2,547position: middledoi
Trastuzumab Deruxtecan in Previously Treated HER2-Positive Breast Cancer
New England Journal of Medicine 2019cited by 1,927position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Fabrice André · Institut Gustave Roussy7 papers (2019–2023)Sibylle Loibl · Breast Center6 papers (2019–2025)Hope S. Rugo · UCSF Helen Diller Family Comprehensive Cancer Center6 papers (2019–2024)Hiroji Iwata · Juntendo University6 papers (2019–2024)Mario Campone · Centre de Recherche en Cancérologie de Lyon5 papers (2019–2022)Ingrid A. Mayer · AstraZeneca (Netherlands)4 papers (2019–2020)Dejan Juric · Harvard University4 papers (2019–2020)David Mills · Kirin (United States)4 papers (2019–2020)Pierfranco Conté · Candiolo Cancer Institute4 papers (2019–2020)Michelle C. Miller · Novartis (United States)3 papers (2020–2020)Bella Kaufman · NYU Langone Health3 papers (2019–2020)Sara M. Tolaney · Medidata (United States)3 papers (2022–2025)Zsuzsanna Pápai · Zrínyi Miklós National Defence University3 papers (2019–2020)Cristina Saura · Fudan University Shanghai Cancer Center3 papers (2019–2025)Masakazu Toi · Universal Scientific Education and Research Network3 papers (2022–2025)Kenichi Inoue · Japan Bio Products (Japan)3 papers (2019–2020)Yeon Hee Park · The Catholic University of Korea Daejeon St. Mary's Hospital3 papers (2019–2024)Yee Soo Chae · Kyungpook National University Hospital3 papers (2024–2025)Masato Takahashi · Hokkaido University Hospital3 papers (2019–2020)Yen‐Shen Lu · National Taiwan University Hospital3 papers (2019–2020)