Area of research
Cancer Research · Genetics
Research interest
Research interests include Glioma Diagnosis and Treatment, RNA modifications and cancer, 3D Printing in Biomedical Research, and Cancer-related molecular mechanisms research.
EGFR promotes ALKBH5 nuclear retention to attenuate N6-methyladenosine and protect against ferroptosis in glioblastoma
Meningioma DNA methylation groups identify biological drivers and therapeutic vulnerabilities
PDGF signaling inhibits mitophagy in glioblastoma stem cells through N-methyladenosine
CHMP2A regulates tumor sensitivity to natural killer cell-mediated cytotoxicity
Superenhancer activation of KLHDC8A drives glioma ciliation and hedgehog signaling
Epitranscriptomic editing of the RNA N6-methyladenosine modification by dCasRx conjugated methyltransferase and demethylase
Targeting glioblastoma signaling and metabolism with a re-purposed brain-penetrant drug
Brd4-bound enhancers drive cell-intrinsic sex differences in glioblastoma
The RNA m6A Reader YTHDF2 Maintains Oncogene Expression and Is a Targetable Dependency in Glioblastoma Stem Cells
Glioblastoma Stem Cells: Driving Resilience through Chaos
Three-dimensional bioprinted glioblastoma microenvironments model cellular dependencies and immune interactions
Zika Virus Targets Glioblastoma Stem Cells through a SOX2-Integrin αvβ5 Axis
CRISPR Screening of CAR T Cells and Cancer Stem Cells Reveals Critical Dependencies for Cell-Based Therapies
The Meningioma Enhancer Landscape Delineates Novel Subgroups and Drives Druggable Dependencies
Cancer Stem Cells: The Architects of the Tumor Ecosystem
Targeting Glioblastoma Stem Cells through Disruption of the Circadian Clock
Targeting pyrimidine synthesis accentuates molecular therapy response in glioblastoma stem cells
Glioma Stem Cell–Specific Superenhancer Promotes Polyunsaturated Fatty-Acid Synthesis to Support EGFR Signaling
Chromatin landscapes reveal developmentally encoded transcriptional states that define human glioblastoma
N-methyladenine DNA Modification in Glioblastoma
Reciprocal Signaling between Glioblastoma Stem Cells and Differentiated Tumor Cells Promotes Malignant Progression
Targeting glioma stem cells through combined BMI1 and EZH2 inhibition
Zika virus has oncolytic activity against glioblastoma stem cells
Therapeutic targeting of ependymoma as informed by oncogenic enhancer profiling
MYC-Regulated Mevalonate Metabolism Maintains Brain Tumor–Initiating Cells