Area of research
Cancer Research · Genetics
Research interest
Research interests include Glioma Diagnosis and Treatment, RNA modifications and cancer, Cancer, Hypoxia, and Metabolism, and Cancer-related molecular mechanisms research.
Metabolic regulation of the glioblastoma stem cell epitranscriptome by malate dehydrogenase 2
Inhibiting DNA-PK induces glioma stem cell differentiation and sensitizes glioblastoma to radiation in mice
The RNA m6A Reader YTHDF2 Maintains Oncogene Expression and Is a Targetable Dependency in Glioblastoma Stem Cells
Zika Virus Targets Glioblastoma Stem Cells through a SOX2-Integrin αvβ5 Axis
CRISPR Screening of CAR T Cells and Cancer Stem Cells Reveals Critical Dependencies for Cell-Based Therapies
Metabolic Regulation of the Epigenome Drives Lethal Infantile Ependymoma
Type I Interferon Regulates a Coordinated Gene Network to Enhance Cytotoxic T Cell–Mediated Tumor Killing
Targeting Glioblastoma Stem Cells through Disruption of the Circadian Clock
Targeting pyrimidine synthesis accentuates molecular therapy response in glioblastoma stem cells
Glioma Stem Cell–Specific Superenhancer Promotes Polyunsaturated Fatty-Acid Synthesis to Support EGFR Signaling
Chromatin landscapes reveal developmentally encoded transcriptional states that define human glioblastoma
N-methyladenine DNA Modification in Glioblastoma
Reciprocal Signaling between Glioblastoma Stem Cells and Differentiated Tumor Cells Promotes Malignant Progression
Ibrutinib inactivates BMX-STAT3 in glioma stem cells to impair malignant growth and radioresistance
Targeting glioma stem cells through combined BMI1 and EZH2 inhibition
Therapeutic targeting of ependymoma as informed by oncogenic enhancer profiling
Transcription elongation factors represent in vivo cancer dependencies in glioblastoma
MYC-Regulated Mevalonate Metabolism Maintains Brain Tumor–Initiating Cells
RBPJ maintains brain tumor–initiating cells through CDK9-mediated transcriptional elongation
Glycosylation, Hypogammaglobulinemia, and Resistance to Viral Infections