Area of research
Epidemiology · Public Health, Environmental and Occupational Health
Research interest
Research interests include Drug, Chagas disease, Mycobacterium tuberculosis, Drug discovery, Computational biology, and Biology.
Perspective on Schistosomiasis Drug Discovery: Highlights from a Schistosomiasis Drug Discovery Workshop at Wellcome Collection, London, September 2022
Short-course combination treatment for experimental chronic Chagas disease
Identification and Optimization of Novel Inhibitors of the Polyketide Synthase 13 Thioesterase Domain with Antitubercular Activity
Lysyl-tRNA synthetase, a target for urgently needed M. tuberculosis drugs
Targeting N-myristoylation for therapy of B-cell lymphomas
Re-evaluating pretomanid analogues for Chagas disease: Hit-to-lead studies reveal both in vitro and in vivo trypanocidal efficacy
Lysyl-tRNA synthetase as a drug target in malaria and cryptosporidiosis
2-Mercapto-Quinazolinones as Inhibitors of Type II NADH Dehydrogenase and <i>Mycobacterium tuberculosis</i>: Structure–Activity Relationships, Mechanism of Action and Absorption, Distribution, Metabolism, and Excretion Characterization
Nitroheterocyclic drugs cure experimental Trypanosoma cruzi infections more effectively in the chronic stage than in the acute stage
Discovery of a Quinoline-4-carboxamide Derivative with a Novel Mechanism of Action, Multistage Antimalarial Activity, and Potent in Vivo Efficacy
Essential but Not Vulnerable: Indazole Sulfonamides Targeting Inosine Monophosphate Dehydrogenase as Potential Leads against<i>Mycobacterium tuberculosis</i>
The anti-tubercular drug delamanid as a potential oral treatment for visceral leishmaniasis
Hit-to-Lead Optimization of a Novel Class of Potent, Broad-Spectrum Trypanosomacides
A novel multiple-stage antimalarial agent that inhibits protein synthesis
C‐reactive protein is essential for innate resistance to pneumococcal infection
Discovery of β2 Adrenergic Receptor Ligands Using Biosensor Fragment Screening of Tagged Wild-Type Receptor
Automated design of ligands to polypharmacological profiles