Area of research
Public Health, Environmental and Occupational Health · Molecular Biology
Research interest
Research focused on Malaria and Druggability, with related work in Drug discovery, Drug, Mycobacterium tuberculosis. Notable publications include 'A novel multiple-stage antimalarial agent that inhibits protein synthesis', 'Lysyl-tRNA synthetase as a drug target in malaria and cryptosporidiosis', and 'MalDA, Accelerating Malaria Drug Discovery'.
Revisiting the Plasmodium falciparum druggable genome using predicted structures and data mining
Different chemical scaffolds bind to L-phe site in Mycobacterium tuberculosis Phe-tRNA synthetase
Perspective on Schistosomiasis Drug Discovery: Highlights from a Schistosomiasis Drug Discovery Workshop at Wellcome Collection, London, September 2022
Identification and Optimization of Novel Inhibitors of the Polyketide Synthase 13 Thioesterase Domain with Antitubercular Activity
Lysyl-tRNA synthetase, a target for urgently needed M. tuberculosis drugs
MalDA, Accelerating Malaria Drug Discovery
Prioritization of Molecular Targets for Antimalarial Drug Discovery
Chemogenomics identifies acetyl-coenzyme A synthetase as a target for malaria treatment and prevention
<i>Mycobacterium tuberculosis</i> Phe-tRNA synthetase: structural insights into tRNA recognition and aminoacylation
Structure of Mycobacterium tuberculosis Phe-tRNA synthetase reveals ligand binding and two-stage tRNA recognition
Lysyl-tRNA synthetase as a drug target in malaria and cryptosporidiosis
Discovery of a Quinoline-4-carboxamide Derivative with a Novel Mechanism of Action, Multistage Antimalarial Activity, and Potent in Vivo Efficacy
A novel multiple-stage antimalarial agent that inhibits protein synthesis