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Damien D. Pearse

University of Miami · US
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Area of research
Pathology and Forensic Medicine · Cellular and Molecular Neuroscience
Research interest
Research interests include Spinal Cord Injury Research, Nerve injury and regeneration, Neurogenesis and neuroplasticity mechanisms, and Nerve Injury and Rehabilitation.
h-index
48
citations
6,955
works
118
NIH funding
primary concept
email

Recent publications

Comparative Profiling of Mouse and Human Microglial Small Extracellular Vesicles Reveals Conserved Core Functions with Distinct miRNA Signatures.
2026cited by 0position: contributordoi
Human Schwann Cell-Derived Extracellular Vesicle Isolation, Bioactivity Assessment, and Omics Characterization
International Journal of Nanomedicine 2025cited by 10position: middledoi
Small Extracellular Vesicles in Neurodegenerative Disease: Emerging Roles in Pathogenesis, Biomarker Discovery, and Therapy
International Journal of Molecular Sciences 2025cited by 7position: lastdoi
Engineered Healing: Synergistic Use of Schwann Cells and Biomaterials for Spinal Cord Regeneration
International Journal of Molecular Sciences 2025cited by 6position: lastdoi
Temporal and Severity-Dependent Alterations in Plasma Extracellular Vesicle Profiles Following Spinal Cord Injury
Cells 2025cited by 3position: lastdoi
The Yin and Yang of Microglia-Derived Extracellular Vesicles in CNS Injury and Diseases
Cells 2024cited by 42position: lastdoi
Treating amyotrophic lateral sclerosis with allogeneic Schwann cell–derived exosomal vesicles: a case report
Neural Regeneration Research 2024cited by 14position: middledoi
Sex Dependent Disparities in the Central Innate Immune Response after Moderate Spinal Cord Contusion in Rat
Cells 2024cited by 11position: lastdoi
Schwann Cell-Derived Exosomal Vesicles: A Promising Therapy for the Injured Spinal Cord
International Journal of Molecular Sciences 2023cited by 36position: lastdoi
Phase 1 Safety Trial of Autologous Human Schwann Cell Transplantation in Chronic Spinal Cord Injury
Journal of Neurotrauma 2021cited by 92position: middledoi
Imaging characteristics of chronic spinal cord injury identified during screening for a cell transplantation clinical trial
Neurosurgical FOCUS 2019cited by 11position: middledoi
Schwann Cell Transplantation Subdues the Pro-Inflammatory Innate Immune Cell Response after Spinal Cord Injury
International Journal of Molecular Sciences 2018cited by 54position: firstdoi
Safety of Autologous Human Schwann Cell Transplantation in Subacute Thoracic Spinal Cord Injury
Journal of Neurotrauma 2017cited by 250position: middledoi
Phosphodiesterase Inhibitors as a Therapeutic Approach to Neuroprotection and Repair
International Journal of Molecular Sciences 2017cited by 83position: lastdoi
Human Schwann cells exhibit long‐term cell survival, are not tumorigenic and promote repair when transplanted into the contused spinal cord
Glia 2017cited by 49position: lastdoi
Identifying the Long-Term Role of Inducible Nitric Oxide Synthase after Contusive Spinal Cord Injury Using a Transgenic Mouse Model
International Journal of Molecular Sciences 2017cited by 19position: lastdoi
Critical data‐based re‐evaluation of minocycline as a putative specific microglia inhibitor
Glia 2016cited by 195position: middledoi
Cyclic AMP is a key regulator of M1 to M2a phenotypic conversion of microglia in the presence of Th2 cytokines
Journal of Neuroinflammation 2016cited by 186position: lastdoi
PDE4B as a microglia target to reduce neuroinflammation
Glia 2016cited by 99position: firstdoi
Regulating Axonal Responses to Injury: The Intersection between Signaling Pathways Involved in Axon Myelination and The Inhibition of Axon Regeneration
Frontiers in Molecular Neuroscience 2016cited by 47position: lastdoi
Use of the CatWalk Gait Device to Assess Differences in Locomotion between Genders in Rats Inherently and following Spinal Cord Injury
Dataset Papers in Science 2016cited by 18position: lastdoi
Schwann cell transplantation for spinal cord injury repair: its significant therapeutic potential and prospectus
Reviews in the Neurosciences 2015cited by 125position: middledoi
The role of the serotonergic system in locomotor recovery after spinal cord injury
Frontiers in Neural Circuits 2015cited by 113position: lastdoi
Female Rats Demonstrate Improved Locomotor Recovery and Greater Preservation of White and Gray Matter after Traumatic Spinal Cord Injury Compared to Males
Journal of Neurotrauma 2015cited by 94position: lastdoi
Therapeutic Hypothermia in Spinal Cord Injury: The Status of Its Use and Open Questions
International Journal of Molecular Sciences 2015cited by 62position: lastdoi
The Interplay between Cyclic AMP, MAPK, and NF-<i>κ</i>B Pathways in Response to Proinflammatory Signals in Microglia
BioMed Research International 2015cited by 58position: lastdoi
MASH1/Ascl1a Leads to GAP43 Expression and Axon Regeneration in the Adult CNS
PLoS ONE 2015cited by 46position: middledoi
The Comparative Utility of Viromer RED and Lipofectamine for Transient Gene Introduction into Glial Cells
BioMed Research International 2015cited by 27position: lastdoi
Peptide-functionalized polymeric nanoparticles for active targeting of damaged tissue in animals with experimental autoimmune encephalomyelitis
Neuroscience Letters 2015cited by 26position: middledoi
Acute Putrescine Supplementation with Schwann Cell Implantation Improves Sensory and Serotonergic Axon Growth and Functional Recovery in Spinal Cord Injured Rats
Neural Plasticity 2015cited by 9position: lastdoi

Grants

No grants ingested yet.

Frequent collaborators

Mousumi Ghosh · University of Miami16 papers (2012–2025)W. Dalton Dietrich · University of Miami12 papers (2012–2025)Mary Barlett Bunge · University of Miami9 papers (2013–2021)Allan D. Levi · University of Miami6 papers (2017–2025)James D. Guest · University of Miami6 papers (2017–2025)Aisha Khan · University of Miami6 papers (2017–2025)Samik Patel · University of Pittsburgh5 papers (2012–2015)Johana Bastidas · Psychogenics (United States)4 papers (2015–2018)Luis M. Tuesta · Sylvester Comprehensive Cancer Center3 papers (2012–2017)Sudheendra N.R. Rao · University of Miami3 papers (2015–2017)Jack Louro · University of Miami3 papers (2012–2015)Eric P. Knott · Miami VA Healthcare System3 papers (2014–2017)Mazen Assi · University of Miami3 papers (2014–2017)Kim D. Anderson · MetroHealth Medical Center3 papers (2017–2021)Alexander Marcillo · University of Miami3 papers (2015–2017)Wai‐Man Chan · Broad Institute3 papers (2012–2017)Efrat Saraf‐Lavi · University of Miami3 papers (2017–2021)P. Anthony Otero · The Ohio State University2 papers (2015–2017)Drew Bleicher · Jackson Memorial Hospital2 papers (2013–2017)Patrick M. Wood · Johns Hopkins University2 papers (2017–2017)
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