← back to search

Christine Van Broeckhoven

KU Leuven · BE
Area of research
Physiology · Neurology
Research interest
Research interests include Biology, Genetics, Amyotrophic lateral sclerosis, Frontotemporal dementia, C9orf72, and Genome-wide association study.
h-index
citations
5,698
works
53
NIH funding
primary concept
email

Recent publications

Author Correction: Common variants in Alzheimer’s disease and risk stratification by polygenic risk scores
Nature Communications 2023cited by 0position: middledoi
Genome-Wide Association Study of Alzheimer’s Disease Brain Imaging Biomarkers and Neuropsychological Phenotypes in the European Medical Information Framework for Alzheimer’s Disease Multimodal Biomarker Discovery Dataset
Frontiers in Aging Neuroscience 2022cited by 49position: middledoi
Prioritization of Drug Targets for Neurodegenerative Diseases by Integrating Genetic and Proteomic Data From Brain and Blood
Biological Psychiatry 2022cited by 49position: middledoi
Lack of association between bridging integrator 1 ( <i>BIN1</i> ) rs744373 polymorphism and tau‐PET load in cognitively intact older adults
Alzheimer s & Dementia Translational Research & Clinical Interventions 2022cited by 4position: middledoi
Common variants in Alzheimer’s disease and risk stratification by polygenic risk scores
Nature Communications 2021cited by 333position: middledoi
Contribution of rare homozygous and compound heterozygous VPS13C missense mutations to dementia with Lewy bodies and Parkinson’s disease
Acta Neuropathologica Communications 2021cited by 43position: lastdoi
TMEM106B and CPOX are genetic determinants of cerebrospinal fluid Alzheimer's disease biomarker levels
Alzheimer s & Dementia 2021cited by 42position: middledoi
Genome-wide association study of Alzheimer’s disease CSF biomarkers in the EMIF-AD Multimodal Biomarker Discovery dataset
Translational Psychiatry 2020cited by 74position: middledoi
Mutated ATP10B increases Parkinson’s disease risk by compromising lysosomal glucosylceramide export
Acta Neuropathologica 2020cited by 64position: lastdoi
Clinical, neuropathological, and genetic characterization of STUB1 variants in cerebellar ataxias: a frequent cause of predominant cognitive impairment
Genetics in Medicine 2020cited by 49position: middledoi
Mendelian randomization implies no direct causal association between leukocyte telomere length and amyotrophic lateral sclerosis
Scientific Reports 2020cited by 10position: middledoi
Loss of DPP6 in neurodegenerative dementia: a genetic player in the dysfunction of neuronal excitability
Acta Neuropathologica 2019cited by 56position: lastdoi
Genetic variation across RNA metabolism and cell death gene networks is implicated in the semantic variant of primary progressive aphasia
Scientific Reports 2019cited by 16position: middledoi
Identification of evolutionarily conserved gene networks mediating neurodegenerative dementia
Nature Medicine 2018cited by 155position: middledoi
The EMIF-AD Multimodal Biomarker Discovery study: design, methods and cohort characteristics
Alzheimer s Research & Therapy 2018cited by 134position: middledoi
An intronic VNTR affects splicing of ABCA7 and increases risk of Alzheimer’s disease
Acta Neuropathologica 2018cited by 101position: middledoi
MRI predictors of amyloid pathology: results from the EMIF-AD Multimodal Biomarker Discovery study
Alzheimer s Research & Therapy 2018cited by 83position: middledoi
A C6orf10/LOC101929163 locus is associated with age of onset in C9orf72 carriers
Brain 2018cited by 51position: middledoi
Male-specific epistasis between WWC1 and TLN2 genes is associated with Alzheimer's disease
Neurobiology of Aging 2018cited by 34position: middledoi
Author Correction: Susceptible genes and disease mechanisms identified in frontotemporal dementia and frontotemporal dementia with Amyotrophic Lateral Sclerosis by DNA-methylation and GWAS
Scientific Reports 2018cited by 2position: middledoi
Deleterious ABCA7 mutations and transcript rescue mechanisms in early onset Alzheimer’s disease
Acta Neuropathologica 2017cited by 74position: middledoi
Identification and description of three families with familial Alzheimer disease that segregate variants in the SORL1 gene
Acta Neuropathologica Communications 2017cited by 69position: middledoi
Clinical Evidence of Disease Anticipation in Families Segregating a <i>C9orf72</i> Repeat Expansion
JAMA Neurology 2017cited by 62position: lastdoi
Susceptible genes and disease mechanisms identified in frontotemporal dementia and frontotemporal dementia with Amyotrophic Lateral Sclerosis by DNA-methylation and GWAS
Scientific Reports 2017cited by 44position: middledoi
NEK1 genetic variability in a Belgian cohort of ALS and ALS-FTD patients
Neurobiology of Aging 2017cited by 44position: middledoi
Drosophila screen connects nuclear transport genes to DPR pathology in c9ALS/FTD
Scientific Reports 2016cited by 280position: middledoi
ATXN2 trinucleotide repeat length correlates with risk of ALS
Neurobiology of Aging 2016cited by 129position: middledoi
A comprehensive study of the genetic impact of rare variants in SORL1 in European early-onset Alzheimer’s disease
Acta Neuropathologica 2016cited by 116position: middledoi
<i>TBK1</i> Mutation Spectrum in an Extended European Patient Cohort with Frontotemporal Dementia and Amyotrophic Lateral Sclerosis
Human Mutation 2016cited by 103position: middledoi
Investigating the role of ALS genes CHCHD10 and TUBA4A in Belgian FTD-ALS spectrum patients
Neurobiology of Aging 2016cited by 74position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Sebastiaan Engelborghs · Vrije Universiteit Brussel15 papers (2012–2021)Rik Vandenberghe · Allen Institute for Brain Science15 papers (2012–2022)Kristel Sleegers · Oslo University Hospital12 papers (2012–2022)Mathieu Vandenbulcke · Allen Institute for Brain Science8 papers (2013–2015)Marc Cruts · KU Leuven8 papers (2013–2017)Peter P. De Deyn · KU Leuven8 papers (2013–2017)Patrick Cras · KU Leuven8 papers (2013–2021)Julie van der Zee · KU Leuven7 papers (2013–2017)Karolien Bettens · University of Antwerp7 papers (2012–2015)Maria Mattheijssens · KU Leuven6 papers (2012–2017)Karin Peeters · KU Leuven6 papers (2012–2017)Anne Sieben · KU Leuven5 papers (2015–2021)Jasper Van Dongen · University of Antwerp5 papers (2012–2018)Ilse Gijselinck · KU Leuven5 papers (2013–2017)Peter Paul De Deyn · Hôpital Broca5 papers (2012–2021)Steven Vermeulen · University of Antwerp4 papers (2012–2015)Caroline Van Cauwenberghe · University of Antwerp4 papers (2013–2015)Jean‐Jacques Martin · KU Leuven4 papers (2015–2021)Tim Van Langenhove · University of Antwerp4 papers (2013–2017)Sara Van Mossevelde · KU Leuven4 papers (2015–2021)