Area of research
Physiology · Neurology
Research interest
Research interests include Biology, Genetics, Amyotrophic lateral sclerosis, Frontotemporal dementia, C9orf72, and Genome-wide association study.
Author Correction: Common variants in Alzheimer’s disease and risk stratification by polygenic risk scores
Genome-Wide Association Study of Alzheimer’s Disease Brain Imaging Biomarkers and Neuropsychological Phenotypes in the European Medical Information Framework for Alzheimer’s Disease Multimodal Biomarker Discovery Dataset
Prioritization of Drug Targets for Neurodegenerative Diseases by Integrating Genetic and Proteomic Data From Brain and Blood
Lack of association between bridging integrator 1 ( <i>BIN1</i> ) rs744373 polymorphism and tau‐PET load in cognitively intact older adults
Common variants in Alzheimer’s disease and risk stratification by polygenic risk scores
Contribution of rare homozygous and compound heterozygous VPS13C missense mutations to dementia with Lewy bodies and Parkinson’s disease
TMEM106B and CPOX are genetic determinants of cerebrospinal fluid Alzheimer's disease biomarker levels
Genome-wide association study of Alzheimer’s disease CSF biomarkers in the EMIF-AD Multimodal Biomarker Discovery dataset
Mutated ATP10B increases Parkinson’s disease risk by compromising lysosomal glucosylceramide export
Clinical, neuropathological, and genetic characterization of STUB1 variants in cerebellar ataxias: a frequent cause of predominant cognitive impairment
Mendelian randomization implies no direct causal association between leukocyte telomere length and amyotrophic lateral sclerosis
Loss of DPP6 in neurodegenerative dementia: a genetic player in the dysfunction of neuronal excitability
Genetic variation across RNA metabolism and cell death gene networks is implicated in the semantic variant of primary progressive aphasia
Identification of evolutionarily conserved gene networks mediating neurodegenerative dementia
The EMIF-AD Multimodal Biomarker Discovery study: design, methods and cohort characteristics
An intronic VNTR affects splicing of ABCA7 and increases risk of Alzheimer’s disease
MRI predictors of amyloid pathology: results from the EMIF-AD Multimodal Biomarker Discovery study
A C6orf10/LOC101929163 locus is associated with age of onset in C9orf72 carriers
Male-specific epistasis between WWC1 and TLN2 genes is associated with Alzheimer's disease
Author Correction: Susceptible genes and disease mechanisms identified in frontotemporal dementia and frontotemporal dementia with Amyotrophic Lateral Sclerosis by DNA-methylation and GWAS
Deleterious ABCA7 mutations and transcript rescue mechanisms in early onset Alzheimer’s disease
Identification and description of three families with familial Alzheimer disease that segregate variants in the SORL1 gene
Clinical Evidence of Disease Anticipation in Families Segregating a <i>C9orf72</i> Repeat Expansion
Susceptible genes and disease mechanisms identified in frontotemporal dementia and frontotemporal dementia with Amyotrophic Lateral Sclerosis by DNA-methylation and GWAS
NEK1 genetic variability in a Belgian cohort of ALS and ALS-FTD patients
Drosophila screen connects nuclear transport genes to DPR pathology in c9ALS/FTD
ATXN2 trinucleotide repeat length correlates with risk of ALS
A comprehensive study of the genetic impact of rare variants in SORL1 in European early-onset Alzheimer’s disease
<i>TBK1</i> Mutation Spectrum in an Extended European Patient Cohort with Frontotemporal Dementia and Amyotrophic Lateral Sclerosis
Investigating the role of ALS genes CHCHD10 and TUBA4A in Belgian FTD-ALS spectrum patients