Area of research
Neurology · Physiology
Research interest
Research focused on C9orf72 and Frontotemporal dementia, with related work in Amyotrophic lateral sclerosis, Cohort, Frontotemporal lobar degeneration. Notable publications include 'Investigating the role of rare heterozygous TREM2 variants in Alzheimer's disease and frontotemporal dementia', 'Loss of TBK1 is a frequent cause of frontotemporal dementia in a Belgian cohort', and 'Mutations in ABCA7 in a Belgian cohort of Alzheimer's disease patients: a targeted resequencing study'.
Unraveling the Immune Signature of Herpes Zoster: Insights Into the Pathophysiology and Human Leukocyte Antigen Risk Profile
Loss of DPP6 in neurodegenerative dementia: a genetic player in the dysfunction of neuronal excitability
Clinical Evidence of Disease Anticipation in Families Segregating a <i>C9orf72</i> Repeat Expansion
Loss of <i>TBK1</i> is a frequent cause of frontotemporal dementia in a Belgian cohort
Mutations in ABCA7 in a Belgian cohort of Alzheimer's disease patients: a targeted resequencing study
Clinical features of<i>TBK1</i>carriers compared with<i>C9orf72</i>,<i>GRN</i>and non-mutation carriers in a Belgian cohort
Rare mutations in SQSTM1 modify susceptibility to frontotemporal lobar degeneration
Investigating the role of rare heterozygous TREM2 variants in Alzheimer's disease and frontotemporal dementia
Distinct Clinical Characteristics of C9orf72 Expansion Carriers Compared With GRN, MAPT, and Nonmutation Carriers in a Flanders-Belgian FTLD Cohort
C9orf72 G4C2 repeat expansions in Alzheimer's disease and mild cognitive impairment
Both common variations and rare non-synonymous substitutions and small insertion/deletions in CLU are associated with increased Alzheimer risk