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Giuseppe Deganutti

University of Padua · IT
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Area of research
Molecular Biology · Cellular and Molecular Neuroscience
Research interest
Research interests include Computer science, Computational biology, Statistical physics, Dynamics (music), G protein-coupled receptor, and Molecular dynamics.
h-index
citations
1,005
works
21
NIH funding
primary concept
email

Recent publications

Hidden GPCR structural transitions addressed by multiple walker supervised molecular dynamics (mwSuMD)
eLife 2025cited by 7position: firstdoi
Author response: Hidden GPCR structural transitions addressed by multiple walker supervised molecular dynamics (mwSuMD)
2025cited by 0position: firstdoi
Hidden GPCR structural transitions addressed by multiple walker supervised molecular dynamics (mwSuMD)
eLife 2025cited by 0position: firstdoi
Author response: Hidden GPCR structural transitions addressed by multiple walker supervised molecular dynamics (mwSuMD)
2025cited by 0position: firstdoi
Hidden GPCR structural transitions addressed by multiple walker supervised molecular dynamics (mwSuMD)
eLife 2024cited by 6position: firstdoi
Hidden GPCR structural transitions addressed by multiple walker supervised molecular dynamics (mwSuMD)
eLife 2024cited by 5position: firstdoi
Hidden GPCR structural transitions addressed by multiple walker supervised molecular dynamics (mwSuMD)
eLife 2024cited by 0position: firstdoi
Author response: Hidden GPCR structural transitions addressed by multiple walker supervised molecular dynamics (mwSuMD)
2024cited by 0position: firstdoi
GWAS of random glucose in 476,326 individuals provide insights into diabetes pathophysiology, complications and treatment stratification
Nature Genetics 2023cited by 100position: middledoi
Hidden GPCR structural transitions addressed by multiple walker supervised molecular dynamics (mwSuMD)
bioRxiv (Cold Spring Harbor Laboratory) 2022cited by 3position: firstdoi
Random glucose GWAS in 493,036 individuals provides insights into diabetes pathophysiology, complications and treatment stratification
medRxiv 2021cited by 9position: middledoi
Activation of the GLP-1 receptor by a non-peptidic agonist
Nature 2020cited by 168position: middledoi
Structure and Dynamics of Adrenomedullin Receptors AM<sub>1</sub> and AM<sub>2</sub> Reveal Key Mechanisms in the Control of Receptor Phenotype by Receptor Activity-Modifying Proteins
ACS Pharmacology & Translational Science 2020cited by 100position: middledoi
A Supervised Molecular Dynamics Approach to Unbiased Ligand–Protein Unbinding
Journal of Chemical Information and Modeling 2020cited by 41position: firstdoi
A2A and A2B adenosine receptors: The extracellular loop 2 determines high (A2A) or low affinity (A2B) for adenosine
Biochemical Pharmacology 2019cited by 42position: middledoi
Cryo-EM structure of the active, Gs-protein complexed, human CGRP receptor
Nature 2018cited by 261position: middledoi
AquaMMapS: An Alternative Tool to Monitor the Role of Water Molecules During Protein–Ligand Association
ChemMedChem 2017cited by 39position: middledoi
Comparison of the Human A<sub>2A</sub> Adenosine Receptor Recognition by Adenosine and Inosine: New Insight from Supervised Molecular Dynamics Simulations
ChemMedChem 2017cited by 27position: firstdoi
Deciphering the Complexity of Ligand–Protein Recognition Pathways Using Supervised Molecular Dynamics (SuMD) Simulations
Journal of Chemical Information and Modeling 2016cited by 98position: middledoi
Understanding allosteric interactions in G protein-coupled receptors using Supervised Molecular Dynamics: A prototype study analysing the human A3 adenosine receptor positive allosteric modulator LUF6000
Bioorganic & Medicinal Chemistry 2015cited by 57position: firstdoi
Exploring the recognition pathway at the human A<sub>2A</sub> adenosine receptor of the endogenous agonist adenosine using supervised molecular dynamics simulations
MedChemComm 2015cited by 42position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Stefano Moro · University of Padua16 papers (2015–2025)Christopher A. Reynolds · University of California, Riverside13 papers (2018–2025)Antonella Ciancetta · University of Padua12 papers (2015–2025) · 9 papers (2022–2025) · 9 papers (2022–2025)Peter B. Griffin · Palo Alto University9 papers (2022–2025) · 7 papers (2022–2025)Alberto Cuzzolin · University of Padua4 papers (2015–2017)Yi-Lynn Liang · Bone Therapeutics3 papers (2018–2020)Laurence J. Miller · Fudan University3 papers (2018–2020)Patrick M. Sexton · Laboratoire de Biologie Physico-Chimique des Protéines Membranaires3 papers (2018–2020)Denise Wootten · Fudan University3 papers (2018–2020)Arthur Christopoulos · ARC Centre of Excellence for Innovations in Peptide and Protein Science3 papers (2018–2020)Cassandra Koole · Rockefeller University2 papers (2018–2020)Sebastian G. B. Furness · Monash University2 papers (2020–2020)Matthew J. Belousoff · Monash University2 papers (2020–2020)Davide Sabbadin · University of Padua2 papers (2015–2016)Madeleine M. Fletcher · Fudan University2 papers (2020–2020) · 2 papers (2020–2020) · 2 papers (2025–2025)
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