Area of research
Molecular Biology · Immunology and Allergy
Research interest
Research interests include Biology, Cell biology, Biochemistry, Medicine, Glutaminase, and Mitochondrion.
A YAP-centered mechanotransduction loop drives collective breast cancer cell invasion
mTORC1 restricts TFE3 activity by auto-regulating its presence on lysosomes
The malate-aspartate shuttle is important for de novo serine biosynthesis
Maintenance of cellular vitamin B6 levels and mitochondrial oxidative function depend on pyridoxal 5′-phosphate homeostasis protein
mTOR-Activating Mutations in RRAGD Are Causative for Kidney Tubulopathy and Cardiomyopathy
Neurodegenerative VPS41 variants inhibit HOPS function and mTORC1‐dependent TFEB/TFE3 regulation
MDH1 deficiency is a metabolic disorder of the malate–aspartate shuttle associated with early onset severe encephalopathy
<i>VPS41</i> recessive mutation causes ataxia and dystonia with retinal dystrophy and mental retardation by inhibiting HOPS function and mTORC1 signaling
Identification of a Loss-of-Function Mutation in the Context of Glutaminase Deficiency and Neonatal Epileptic Encephalopathy
GLS hyperactivity causes glutamate excess, infantile cataract and profound developmental delay
Lysine methylation by the mitochondrial methyltransferase FAM173B optimizes the function of mitochondrial ATP synthase
A Systematic Analysis of Oncogenic Gene Fusions in Primary Colon Cancer
CYFIP1 Coordinates mRNA Translation and Cytoskeleton Remodeling to Ensure Proper Dendritic Spine Formation
Control of Epithelial Cell Migration and Invasion by the IKKβ- and CK1α-Mediated Degradation of RAPGEF2
Rap2A links intestinal cell polarity to brush border formation