Area of research
Genetics · Molecular Biology
Research interest
Research interests include Genetic Associations and Epidemiology, Genomics and Rare Diseases, Epigenetics and DNA Methylation, and Bioinformatics and Genomic Networks.
Sequencing in over 50,000 cases identifies coding and structural variation underlying atrial fibrillation risk
Validation of human telomere length multi-ancestry meta-analysis association signals identifies POP5 and KBTBD6 as human telomere length regulation genes
Clonal haematopoiesis and risk of chronic liver disease
Association Between Whole Blood–Derived Mitochondrial DNA Copy Number, Low‐Density Lipoprotein Cholesterol, and Cardiovascular Disease Risk
Epigenome-wide DNA methylation association study of circulating IgE levels identifies novel targets for asthma
The genetic determinants of recurrent somatic mutations in 43,693 blood genomes
Author Correction: Clonal haematopoiesis and risk of chronic liver disease
A framework for detecting noncoding rare-variant associations of large-scale whole-genome sequencing studies
Mendelian randomization supports bidirectional causality between telomere length and clonal hematopoiesis of indeterminate potential
Whole Genome Association Study of the Plasma Metabolome Identifies Metabolites Linked to Cardiometabolic Disease in Black Individuals
Powerful, scalable and resource-efficient meta-analysis of rare variant associations in large whole genome sequencing studies
Whole genome sequencing identifies structural variants contributing to hematologic traits in the NHLBI TOPMed program
Sequencing of 53,831 diverse genomes from the NHLBI TOPMed Program
Pangenomics enables genotyping of known structural variants in 5202 diverse genomes
A high-resolution HLA reference panel capturing global population diversity enables multi-ancestry fine-mapping in HIV host response
Association of mitochondrial DNA copy number with cardiometabolic diseases
Genome sequencing unveils a regulatory landscape of platelet reactivity
Whole-genome sequencing association analysis of quantitative red blood cell phenotypes: The NHLBI TOPMed program
Whole-genome association analyses of sleep-disordered breathing phenotypes in the NHLBI TOPMed program
Robust, flexible, and scalable tests for Hardy–Weinberg equilibrium across diverse ancestries
Whole-genome sequencing in diverse subjects identifies genetic correlates of leukocyte traits: The NHLBI TOPMed program
Presence and transmission of mitochondrial heteroplasmic mutations in human populations of European and African ancestry
Variant-specific inflation factors for assessing population stratification at the phenotypic variance level
Dynamic incorporation of multiple in silico functional annotations empowers rare variant association analysis of large whole-genome sequencing studies at scale
Asthma and its relationship to mitochondrial copy number: Results from the Asthma Translational Genomics Collaborative (ATGC) of the Trans-Omics for Precision Medicine (TOPMed) program
Mapping the 17q12–21.1 Locus for Variants Associated with Early-Onset Asthma in African Americans
Sequencing of 53,831 diverse genomes from the NHLBI TOPMed Program
Exome sequencing of 20,791 cases of type 2 diabetes and 24,440 controls
Association Between Titin Loss-of-Function Variants and Early-Onset Atrial Fibrillation
Deep-coverage whole genome sequences and blood lipids among 16,324 individuals