Area of research
Genetics · Surgery
Research interest
Research interests include Genetic Associations and Epidemiology, Lipoproteins and Cardiovascular Health, Lipid metabolism and disorders, and Diabetes, Cardiovascular Risks, and Lipoproteins.
Discovery and systematic characterization of risk variants and genes for coronary artery disease in over a million participants
Gene Sequencing Identifies Perturbation in Nitric Oxide Signaling as a Nonlipid Molecular Subtype of Coronary Artery Disease
In vivo CRISPR base editing of PCSK9 durably lowers cholesterol in primates
Genetic Architecture of Abdominal Aortic Aneurysm in the Million Veteran Program
Limitations of Contemporary Guidelines for Managing Patients at High Genetic Risk of Coronary Artery Disease
Association of Genetic Variation With Cirrhosis: A Multi-Trait Genome-Wide Association and Gene–Environment Interaction Study
Heterozygous <i>ABCG5</i> Gene Deficiency and Risk of Coronary Artery Disease
Single-Cell Analysis of the Normal Mouse Aorta Reveals Functionally Distinct Endothelial Cell Populations
Polygenic background modifies penetrance of monogenic variants conferring risk for coronary artery disease, breast cancer, or colorectal cancer
Association Between Titin Loss-of-Function Variants and Early-Onset Atrial Fibrillation
Polygenic Risk Score Identifies Subgroup With Higher Burden of Atherosclerosis and Greater Relative Benefit From Statin Therapy in the Primary Prevention Setting
Fifteen new risk loci for coronary artery disease highlight arterial-wall-specific mechanisms
Heritability of Atrial Fibrillation
Genetic Risk, Adherence to a Healthy Lifestyle, and Coronary Disease
Rare variant in scavenger receptor BI raises HDL cholesterol and increases risk of coronary heart disease
Risk prediction by genetic risk scores for coronary heart disease is independent of self-reported family history
Genetically Determined Height and Coronary Artery Disease
Systems Genetics Analysis of Genome-Wide Association Study Reveals Novel Associations Between Key Biological Processes and Coronary Artery Disease
Genetic variants primarily associated with type 2 diabetes are related to coronary artery disease risk
Searching for missing heritability: Designing rare variant association studies
Exome sequencing identifies rare LDLR and APOA5 alleles conferring risk for myocardial infarction
Integrative Genomics Reveals Novel Molecular Pathways and Gene Networks for Coronary Artery Disease
Shared Genetic Susceptibility to Ischemic Stroke and Coronary Artery Disease
Best Practices and Joint Calling of the HumanExome BeadChip: The CHARGE Consortium
Bayesian inference analyses of the polygenic architecture of rheumatoid arthritis
Genome-wide association study in Han Chinese identifies four new susceptibility loci for coronary artery disease
Prevalence of ANGPTL3 and APOB Gene Mutations in Subjects With Combined Hypolipidemia
Multi-Ethnic Analysis of Lipid-Associated Loci: The NHLBI CARe Project
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