Area of research
Biochemistry · Oncology
Research interest
Research interests include Biology, Cell biology, Major facilitator superfamily, Microcephaly, Mutation, and Transporter.
Mfsd2a utilizes a flippase mechanism to mediate omega-3 fatty acid lysolipid transport
Blood-derived lysophospholipid sustains hepatic phospholipids and fat storage necessary for hepatoprotection in overnutrition
Spns1 is a lysophospholipid transporter mediating lysosomal phospholipid salvage
Destabilization of β Cell FIT2 by saturated fatty acids alter lipid droplet numbers and contribute to ER stress and diabetes
The lipid transporter Mfsd2a maintains pulmonary surfactant homeostasis
Structural basis of omega-3 fatty acid transport across the blood–brain barrier
High-Density Lipoprotein 3 Cholesterol and Primary Open-Angle Glaucoma
Single-Cell Analysis of Blood-Brain Barrier Response to Pericyte Loss
Biallelic MFSD2A variants associated with congenital microcephaly, developmental delay, and recognizable neuroimaging features
The lysolipid transporter Mfsd2a regulates lipogenesis in the developing brain
LRH-1 regulates hepatic lipid homeostasis and maintains arachidonoyl phospholipid pools critical for phospholipid diversity
Mfsd2b is essential for the sphingosine-1-phosphate export in erythrocytes and platelets
Mfsd2a Is a Transporter for the Essential ω-3 Fatty Acid Docosahexaenoic Acid (DHA) in Eye and Is Important for Photoreceptor Cell Development
A mutation of<i>EPT1 (SELENOI)</i>underlies a new disorder of Kennedy pathway phospholipid biosynthesis
Structural Insights into the Transport Mechanism of the Human Sodium-dependent Lysophosphatidylcholine Transporter MFSD2A
Inactivating mutations in MFSD2A, required for omega-3 fatty acid transport in brain, cause a lethal microcephaly syndrome
A partially inactivating mutation in the sodium-dependent lysophosphatidylcholine transporter MFSD2A causes a non-lethal microcephaly syndrome
MicroRNAs Are Required for the Feature Maintenance and Differentiation of Brown Adipocytes
CCAAT/enhancer binding protein α predicts poorer prognosis and prevents energy starvation–induced cell death in hepatocellular carcinoma
Fat Storage-inducing Transmembrane Protein 2 Is Required for Normal Fat Storage in Adipose Tissue