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Markus R. Wenk

National University of Singapore · SG
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Area of research
Molecular Biology · Biochemistry
Research interest
Research focused on Lipidomics and Lipidome, with related work in Neuroscience, Endoplasmic reticulum, Biochemistry. Notable publications include 'PI4P/phosphatidylserine countertransport at ORP5- and ORP8-mediated ER–plasma membrane contacts', 'Harmonizing lipidomics: NIST interlaboratory comparison exercise for lipidomics using SRM 1950–Metabolites in Frozen Human Plasma', and 'The Transcription Factor STAT-1 Couples Macrophage Synthesis of 25-Hydroxycholesterol to the Interferon Antiviral Response'.
h-index
citations
9,578
works
94
NIH funding
primary concept
email

Recent publications

Technical recommendations for analyzing oxylipins by liquid chromatography–mass spectrometry
Science Signaling 2025cited by 29position: middledoi
Introduction of a lipidomics scoring system for data quality assessment
Journal of Lipid Research 2025cited by 4position: middledoi
Lipidome atlas of the adult human brain
Nature Communications 2024cited by 96position: middledoi
The lipidomics reporting checklist a framework for transparency of lipidomic experiments and repurposing resource data
Journal of Lipid Research 2024cited by 41position: middledoi
Concordant inter-laboratory derived concentrations of ceramides in human plasma reference materials via authentic standards
Nature Communications 2024cited by 25position: lastdoi
MFSD7c functions as a transporter of choline at the blood–brain barrier
Cell Research 2024cited by 20position: middledoi
Advances in clinical application of lipidomics in healthy ageing and healthy longevity medicine
Ageing Research Reviews 2024cited by 10position: middledoi
iPS-cell-derived microglia promote brain organoid maturation via cholesterol transfer
Nature 2023cited by 195position: middledoi
Mfsd2a utilizes a flippase mechanism to mediate omega-3 fatty acid lysolipid transport
Proceedings of the National Academy of Sciences 2023cited by 42position: middledoi
Lipidomics profiling reveals distinct patterns of plasma sphingolipid alterations in Alzheimer’s disease and vascular dementia
Alzheimer s Research & Therapy 2023cited by 36position: middledoi
Lysosomal phospholipase A2 contributes to the biosynthesis of the atypical late endosome lipid bis(monoacylglycero)phosphate
Communications Biology 2023cited by 33position: middledoi
Diacylglycerol at the inner nuclear membrane fuels nuclear envelope expansion in closed mitosis
Journal of Cell Science 2023cited by 32position: middledoi
Plasma lipidomic profiling reveals metabolic adaptations to pregnancy and signatures of cardiometabolic risk: a preconception and longitudinal cohort study
BMC Medicine 2023cited by 31position: lastdoi
Blood-derived lysophospholipid sustains hepatic phospholipids and fat storage necessary for hepatoprotection in overnutrition
Journal of Clinical Investigation 2023cited by 27position: middledoi
Brain lipidomics: From functional landscape to clinical significance
Science Advances 2022cited by 291position: middledoi
Lipidomic profiling of human serum enables detection of pancreatic cancer
Nature Communications 2022cited by 171position: middledoi
Introducing the Lipidomics Minimal Reporting Checklist
Nature Metabolism 2022cited by 89position: middledoi
Spns1 is a lysophospholipid transporter mediating lysosomal phospholipid salvage
Proceedings of the National Academy of Sciences 2022cited by 63position: middledoi
Destabilization of β Cell FIT2 by saturated fatty acids alter lipid droplet numbers and contribute to ER stress and diabetes
Proceedings of the National Academy of Sciences 2022cited by 51position: middledoi
Population-based plasma lipidomics reveals developmental changes in metabolism and signatures of obesity risk: a mother-offspring cohort study
BMC Medicine 2022cited by 40position: middledoi
Clinical variable-based cluster analysis identifies novel subgroups with a distinct genetic signature, lipidomic pattern and cardio-renal risks in Asian patients with recent-onset type 2 diabetes
Diabetologia 2022cited by 32position: middledoi
The lipid transporter Mfsd2a maintains pulmonary surfactant homeostasis
Journal of Biological Chemistry 2022cited by 25position: middledoi
Recommendations for good practice in MS-based lipidomics
Journal of Lipid Research 2021cited by 183position: middledoi
Sphingolipid metabolism during Toll‐like receptor 4 (TLR4)‐mediated macrophage activation
British Journal of Pharmacology 2021cited by 131position: middledoi
Quality control requirements for the correct annotation of lipidomics data
Nature Communications 2021cited by 104position: middledoi
Fatty acid oxidation is a druggable gateway regulating cellular plasticity for driving metastasis in breast cancer
Science Advances 2021cited by 99position: middledoi
TDP-43 mediates SREBF2-regulated gene expression required for oligodendrocyte myelination
The Journal of Cell Biology 2021cited by 52position: middledoi
A reference map of sphingolipids in murine tissues
Cell Reports 2021cited by 49position: middledoi
LICAR: An Application for Isotopic Correction of Targeted Lipidomic Data Acquired with Class-Based Chromatographic Separations Using Multiple Reaction Monitoring
Analytical Chemistry 2021cited by 36position: middledoi
Profiling the Lipidome requires quality control
Zenodo (CERN European Organization for Nuclear Research) 2021cited by 0position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Federico Torta · National University of Singapore26 papers (2014–2023)Guanghou Shui · National University of Singapore23 papers (2012–2015)Amaury Cazenave‐Gassiot · National University of Singapore22 papers (2015–2024)David L. Silver · National University of Singapore13 papers (2015–2023)Wei Fun Cheong · National University of Singapore9 papers (2012–2017)Juat Chin Foo · National University of Singapore7 papers (2016–2024) · 6 papers (2018–2025) · 6 papers (2017–2025)Robert Ahrends · Max Planck Institute of Molecular Cell Biology and Genetics6 papers (2019–2025)Gerhard Liebisch · University Hospital Regensburg6 papers (2018–2025)Bernice H. Wong · National University of Singapore6 papers (2015–2023)Lukas B. Tanner · National University of Singapore6 papers (2012–2015)Long N. Nguyen · National University of Singapore5 papers (2015–2024)Xianlin Han · The University of Texas Health Science Center at Houston5 papers (2018–2025)Bryan C. Tan · National University of Singapore5 papers (2015–2023)Bo Burla · National University of Singapore5 papers (2018–2021)Dwight L.A. Galam · National University of Singapore5 papers (2016–2023) · 5 papers (2019–2025)Sneha Muralidharan · National University of Singapore4 papers (2021–2022)Christer S. Ejsing · European Molecular Biology Laboratory4 papers (2019–2021)
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