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Vivianna M. Van Deerlin

Institute on Aging ·
🔎 Find collaborators in Neurology · Physiology →
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Area of research
Neurology · Physiology
Research interest
Research interests include Amyotrophic Lateral Sclerosis Research, Parkinson's Disease Mechanisms and Treatments, Alzheimer's disease research and treatments, and Neurological diseases and metabolism.
h-index
100
citations
40,691
works
362
NIH funding
primary concept
Medicine
email

Recent publications

TDP-43 loss induces cryptic polyadenylation in ALS/FTD
Nature Neuroscience 2025cited by 16position: middledoi
Copy Number Variation and Haplotype Analysis of <scp>17q21.31</scp> Reveals Increased Risk Associated with Progressive Supranuclear Palsy and Gene Expression Changes in Neuronal Cells
Movement Disorders 2025cited by 1position: middledoi
MAPT H2 haplotype and risk of Pick's disease in the Pick's disease International Consortium: a genetic association study
The Lancet Neurology 2024cited by 23position: middledoi
Author Correction: TDP-43 loss and ALS-risk SNPs drive mis-splicing and depletion of UNC13A
Nature 2024cited by 4position: middledoi
Association of Structural Forms of 17q21.31 with the Risk of Progressive Supranuclear Palsy and <i>MAPT</i> Sub-haplotypes
medRxiv 2024cited by 0position: middledoi
TDP-43 loss and ALS-risk SNPs drive mis-splicing and depletion of UNC13A
Nature 2022cited by 499position: middledoi
Prioritization of Drug Targets for Neurodegenerative Diseases by Integrating Genetic and Proteomic Data From Brain and Blood
Biological Psychiatry 2022cited by 49position: middledoi
Common Variants Near <scp>ZIC1</scp> and <scp>ZIC4</scp> in Autopsy‐Confirmed Multiple System Atrophy
Movement Disorders 2022cited by 15position: middledoi
Genome sequencing analysis identifies new loci associated with Lewy body dementia and provides insights into its genetic architecture
Nature Genetics 2021cited by 475position: middledoi
Genomewide Association Studies of <scp> <i>LRRK2</i> </scp> Modifiers of Parkinson's Disease
Annals of Neurology 2021cited by 49position: middledoi
Differences in the Presentation and Progression of Parkinson's Disease by Sex
Movement Disorders 2020cited by 100position: middledoi
Analysis of neurodegenerative disease-causing genes in dementia with Lewy bodies
Acta Neuropathologica Communications 2020cited by 42position: middledoi
Machine learning suggests polygenic risk for cognitive dysfunction in amyotrophic lateral sclerosis
EMBO Molecular Medicine 2020cited by 27position: middledoi
Postmortem Cortex Samples Identify Distinct Molecular Subtypes of ALS: Retrotransposon Activation, Oxidative Stress, and Activated Glia
Cell Reports 2019cited by 328position: middledoi
Genomewide association study of Parkinson's disease clinical biomarkers in 12 longitudinal patients' cohorts
Movement Disorders 2019cited by 189position: middledoi
<i>TMEM106B</i> Effect on cognition in Parkinson disease and frontotemporal dementia
Annals of Neurology 2019cited by 87position: middledoi
Primary Tau Pathology, Not Copathology, Correlates With Clinical Symptoms in PSP and CBD
Journal of Neuropathology & Experimental Neurology 2019cited by 68position: middledoi
C9orf72 intermediate repeats are associated with corticobasal degeneration, increased C9orf72 expression and disruption of autophagy
Acta Neuropathologica 2019cited by 60position: middledoi
Heritability and genetic variance of dementia with Lewy bodies
Neurobiology of Disease 2019cited by 44position: middledoi
Genetic variation across RNA metabolism and cell death gene networks is implicated in the semantic variant of primary progressive aphasia
Scientific Reports 2019cited by 16position: middledoi
Analysis of shared heritability in common disorders of the brain
Science 2018cited by 2,016position: middledoi
Neurodegenerative disease concomitant proteinopathies are prevalent, age-related and APOE4-associated
Brain 2018cited by 729position: middledoi
Identification of evolutionarily conserved gene networks mediating neurodegenerative dementia
Nature Medicine 2018cited by 155position: middledoi
Sex-specific genetic predictors of Alzheimer’s disease biomarkers
Acta Neuropathologica 2018cited by 117position: middledoi
Selective Genetic Overlap Between Amyotrophic Lateral Sclerosis and Diseases of the Frontotemporal Dementia Spectrum
JAMA Neurology 2018cited by 95position: middledoi
P1‐139: THE CONTRIBUTION OF SEX‐SPECIFIC ASSOCIATIONS IN GENETIC STUDIES OF ALZHEIMER'S DISEASE PATHOLOGY
Alzheimer s & Dementia 2018cited by 0position: middledoi
Investigating the genetic architecture of dementia with Lewy bodies: a two-stage genome-wide association study
The Lancet Neurology 2017cited by 286position: middledoi
Genome-wide association study identifies four novel loci associated with Alzheimer’s endophenotypes and disease modifiers
Acta Neuropathologica 2017cited by 252position: middledoi
Susceptible genes and disease mechanisms identified in frontotemporal dementia and frontotemporal dementia with Amyotrophic Lateral Sclerosis by DNA-methylation and GWAS
Scientific Reports 2017cited by 44position: middledoi
Large-scale exploratory genetic analysis of cognitive impairment in Parkinson's disease
Neurobiology of Aging 2017cited by 37position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

John Q. Trojanowski · University of Pennsylvania13 papers (2012–2019)Murray Grossman · University of Pennsylvania11 papers (2012–2019)Virginia M.‐Y. Lee · Behavioral Health Services7 papers (2012–2019)David J. Irwin · University of Pennsylvania7 papers (2013–2019)Sharon X. Xie · University of Pennsylvania5 papers (2015–2019)EunRan Suh · Institute on Aging5 papers (2013–2019)Edward B. Lee · University of California, Davis5 papers (2013–2019)Alice Chen‐Plotkin · University of Pennsylvania4 papers (2012–2019)Jon B. Toledo · Houston Methodist4 papers (2013–2016)Howard I. Hurtig · California University of Pennsylvania4 papers (2012–2016)Daniel Weintraub · California University of Pennsylvania4 papers (2014–2019)Bruce L. Miller · University at Buffalo, State University of New York3 papers (2015–2019)James B. Leverenz · Cleveland Clinic3 papers (2014–2017)Leo McCluskey · Cardiff and Vale University Health Board3 papers (2012–2015)John Robinson · University of Wolverhampton3 papers (2013–2019)Thomas J. Montine · Stanford University3 papers (2014–2017)Lauren Elman · Valve (United States)3 papers (2012–2015)Joseph F. Quinn · Oregon Health & Science University3 papers (2014–2017)Steven E. Arnold · Massachusetts General Hospital3 papers (2012–2015)Johannes Brettschneider · University of Pennsylvania3 papers (2013–2016)
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