Area of research
Molecular Biology · Hematology
Research interest
Research interests include Protein Degradation and Inhibitors, Acute Myeloid Leukemia Research, Histone Deacetylase Inhibitors Research, and Multiple Myeloma Research and Treatments.
KAT6A and KAT7 Histone Acetyltransferase Complexes Are Molecular Dependencies and Therapeutic Targets in <i>NUP98</i> -Rearranged Acute Myeloid Leukemia
Combined inhibition of KAT6A/B and Menin reverses estrogen receptor-driven gene expression programs in breast cancer
p300/CBP is an essential driver of pathogenic enhancer activity and gene expression in Ewing sarcoma
Mezigdomide is effective alone and in combination with menin inhibition in preclinical models of <i>KMT2A</i>-r and <i>NPM1c</i> AML
Mutant NPM1 Directly Regulates Oncogenic Transcription in Acute Myeloid Leukemia
IKAROS and MENIN coordinate therapeutically actionable leukemogenic gene expression in MLL-r acute myeloid leukemia
The menin-MLL1 interaction is a molecular dependency in <i>NUP98</i>-rearranged AML
Therapeutic targeting of preleukemia cells in a mouse model of <i>NPM1</i> mutant acute myeloid leukemia
Addendum: The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity
Loss of ATRX, Genome Instability, and an Altered DNA Damage Response Are Hallmarks of the Alternative Lengthening of Telomeres Pathway