Area of research
Cancer Research · Molecular Biology
Research interest
Research interests include MicroRNA in disease regulation, NF-κB Signaling Pathways, RNA Research and Splicing, and RNA modifications and cancer.
The thymocyte-specific RNA-binding protein Arpp21 provides TCR repertoire diversity by binding to the 3’-UTR and promoting Rag1 mRNA expression
Impaired neurogenesis alters brain biomechanics in a neuroprogenitor-based genetic subtype of congenital hydrocephalus
The RNA-binding protein ARPP21 controls dendritic branching by functionally opposing the miRNA it hosts
The ubiquitin ligase LIN41/TRIM71 targets p53 to antagonize cell death and differentiation pathways during stem cell differentiation
Lin41/Trim71 is essential for mouse development and specifically expressed in postnatal ependymal cells of the brain
An unconventional role for miRNA: let-7 activates Toll-like receptor 7 and causes neurodegeneration
Expression of Toll-Like Receptors in the Developing Brain