Area of research
Physiology · Molecular Biology
Research interest
Research interests include Telomeres, Telomerase, and Senescence, DNA Repair Mechanisms, Protein Structure and Dynamics, and RNA and protein synthesis mechanisms.
SMARCA4 regulates the NK-mediated killing of senescent cells.
Guidelines for minimal information on cellular senescence experimentation in vivo
Premature thymic functional senescence is a hallmark of childhood acute lymphoblastic leukemia survivorship.
A defective splicing machinery promotes senescence through MDM4 alternative splicing.
Defining melanoma combination therapies that provide senolytic sensitivity in human melanoma cells
53BP1 mediates sensitivity to chemotherapy and is associated with poor clinical outcomes in high-grade serous ovarian cancer
Supplementary Figure from Targeting IKKε in Androgen-Independent Prostate Cancer Causes Phenotypic Senescence and Genomic Instability
A senescence-like state is beneficial for ovarian cancer treatment
Supplementary Data from Targeting IKKε in Androgen-Independent Prostate Cancer Causes Phenotypic Senescence and Genomic Instability
Data from Targeting IKKε in Androgen-Independent Prostate Cancer Causes Phenotypic Senescence and Genomic Instability
Supplementary Data from Targeting IKKε in Androgen-Independent Prostate Cancer Causes Phenotypic Senescence and Genomic Instability
Data from Targeting IKKε in Androgen-Independent Prostate Cancer Causes Phenotypic Senescence and Genomic Instability
Supplementary Figure from Targeting IKKε in Androgen-Independent Prostate Cancer Causes Phenotypic Senescence and Genomic Instability
Targeting IKKε in Androgen-Independent Prostate Cancer Causes Phenotypic Senescence and Genomic Instability.
Senolytic Targeting of Bcl-2 Anti-Apoptotic Family Increases Cell Death in Irradiated Sarcoma Cells.
Homologous recombination-mediated irreversible genome damage underlies telomere-induced senescence.
NCOR1 Sustains Colorectal Cancer Cell Growth and Protects against Cellular Senescence.
Non-canonical ATM/MRN activities temporally define the senescence secretory program.
Dual Inhibition of Autophagy and PI3K/AKT/MTOR Pathway as a Therapeutic Strategy in Head and Neck Squamous Cell Carcinoma.
Exploiting interconnected synthetic lethal interactions between PARP inhibition and cancer cell reversible senescence.
Targetable mechanisms driving immunoevasion of persistent senescent cells link chemotherapy-resistant cancer to aging
Assessing Functional Roles of the Senescence-Associated Secretory Phenotype (SASP).
Quantifying Senescence-Associated Phenotypes in Primary Multipotent Mesenchymal Stromal Cell Cultures.
An Essential Role for Senescent Cells in Optimal Wound Healing through Secretion of PDGF-AA