Area of research
Molecular Biology · Developmental Neuroscience
Research interest
Research interests include Single-cell and spatial transcriptomics, Neurogenesis and neuroplasticity mechanisms, Neuroinflammation and Neurodegeneration Mechanisms, and RNA Research and Splicing.
Anoctamin-2-specific T cells link Epstein-Barr virus to multiple sclerosis
Quantitative characterization of cell niches in spatially resolved omics data
Spatial dynamics of brain development and neuroinflammation
Cellular architecture of evolving neuroinflammatory lesions and multiple sclerosis pathology
Oligodendrocytes produce amyloid-β and contribute to plaque formation alongside neurons in Alzheimer’s disease model mice
Whole-brain spatial transcriptional analysis at cellular resolution
snRNA-seq stratifies multiple sclerosis patients into distinct white matter glial responses
Developmental origin of oligodendrocytes determines their function in the adult brain
Opportunities and challenges of single-cell and spatially resolved genomics methods for neuroscience discovery
Disease-associated oligodendroglia: a putative nexus in neurodegeneration
Spatial epigenome–transcriptome co-profiling of mammalian tissues
Brain matters: unveiling the distinct contributions of region, age, and sex to glia diversity and CNS function
Spatial profiling of chromatin accessibility in mouse and human tissues
Spatial-CUT&Tag: Spatially resolved chromatin modification profiling at the cellular level
Cell-type-specific cis-eQTLs in eight human brain cell types identify novel risk genes for psychiatric and neurological disorders
Multimodal chromatin profiling using nanobody-based single-cell CUT&Tag
Epigenomic priming of immune genes implicates oligodendroglia in multiple sclerosis susceptibility
Developmental landscape of human forebrain at a single-cell level identifies early waves of oligodendrogenesis
Spatial and temporal heterogeneity in the lineage progression of fine oligodendrocyte subtypes
Single-cell CUT&Tag profiles histone modifications and transcription factors in complex tissues
Cell-type specialization is encoded by specific chromatin topologies
Functionally distinct subgroups of oligodendrocyte precursor cells integrate neural activity and execute myelin formation
Distinct oligodendrocyte populations have spatial preference and different responses to spinal cord injury
RADICL-seq identifies general and cell type–specific principles of genome-wide RNA-chromatin interactions
Crossing boundaries: Interplay between the immune system and oligodendrocyte lineage cells
Gsta4 controls apoptosis of differentiating adult oligodendrocytes during homeostasis and remyelination via the mitochondria-associated Fas-Casp8-Bid-axis
Altered human oligodendrocyte heterogeneity in multiple sclerosis
An Atlas of Vagal Sensory Neurons and Their Molecular Specialization
PAD2-Mediated Citrullination Contributes to Efficient Oligodendrocyte Differentiation and Myelination
Oligodendrocyte Intrinsic miR-27a Controls Myelination and Remyelination