Area of research
Neurology · Cellular and Molecular Neuroscience
Research interest
Research interests include Neuroscience and Neuropharmacology Research, Parkinson's Disease Mechanisms and Treatments, Amino Acid Enzymes and Metabolism, and Tryptophan and brain disorders.
Absence of Ledgf in mouse brain affects the Kmt2a/b and polycomb balance, synaptic transmission and motor function
Loss of the lysosomal lipid flippase ATP10B leads to progressive dopaminergic neurodegeneration and parkinsonian motor deficits
The G2019S LRRK2 mutation exacerbates α-synuclein and tau neuropathology through divergent pathways in Parkinson’s disease models
Loss of the lysosomal lipid flippase ATP10B leads to progressive dopaminergic neurodegeneration and Parkinsonian motor deficits
Differential genetic associations and expression of PAPST1/SLC35B2 in bipolar disorder and schizophrenia
Rodent models based on endolysosomal genes involved in Parkinson's disease
Corticostriatal dysfunction and social interaction deficits in mice lacking the cystine/glutamate antiporter
Measurement of lactate levels in postmortem brain, iPSCs, and animal models of schizophrenia
Kinase network dysregulation in a human induced pluripotent stem cell model of DISC1 schizophrenia
Connectivity Analyses of Bioenergetic Changes in Schizophrenia: Identification of Novel Treatments
Absence of system xc − on immune cells invading the central nervous system alleviates experimental autoimmune encephalitis
Nigral proteasome inhibition in mice leads to motor and non-motor deficits and increased expression of Ser129 phosphorylated α-synuclein
Comparative analysis of antibodies to xCT (Slc7a11): Forewarned is forearmed