Area of research
Genetics · Physiology
Research interest
Research interests include Lysosomal Storage Disorders Research, Parkinson's Disease Mechanisms and Treatments, Genetics and Neurodevelopmental Disorders, and Cellular transport and secretion.
Loss of the lysosomal lipid flippase ATP10B leads to progressive dopaminergic neurodegeneration and parkinsonian motor deficits
The G2019S LRRK2 mutation exacerbates α-synuclein and tau neuropathology through divergent pathways in Parkinson’s disease models
Loss of the lysosomal lipid flippase ATP10B leads to progressive dopaminergic neurodegeneration and Parkinsonian motor deficits
Rodent models based on endolysosomal genes involved in Parkinson's disease
Functional analysis of <i>TLK2</i> variants and their proximal interactomes implicates impaired kinase activity and chromatin maintenance defects in their pathogenesis