Area of research
Molecular Biology · Genetics
Research interest
Research interests include CRISPR and Genetic Engineering, Virus-based gene therapy research, CAR-T cell therapy research, and RNA Interference and Gene Delivery.
Peptide-enabled ribonucleoprotein delivery for CRISPR engineering (PERC) in primary human immune cells and hematopoietic stem cells
Peptide-mediated delivery of CRISPR enzymes for the efficient editing of primary human lymphocytes
High-yield genome engineering in primary cells using a hybrid ssDNA repair template and small-molecule cocktails
Targeted delivery of CRISPR-Cas9 and transgenes enables complex immune cell engineering
A diagnostic host response biosignature for COVID-19 from RNA profiling of nasal swabs and blood
Constrained chromatin accessibility in PU.1-mutated agammaglobulinemia patients
Abcc1 and Ggt5 support lymphocyte guidance through export and catabolism of <i>S</i> -geranylgeranyl- <scp>l</scp> -glutathione
Evaluation of SARS-CoV-2 serology assays reveals a range of test performance
Pooled Knockin Targeting for Genome Engineering of Cellular Immunotherapies
SARS-CoV-2 seroprevalence and neutralizing activity in donor and patient blood
Timed inhibition of CDC7 increases CRISPR-Cas9 mediated templated repair
Functional CRISPR dissection of gene networks controlling human regulatory T cell identity
Polymer-stabilized Cas9 nanoparticles and modified repair templates increase genome editing efficiency
Regulatory T cells use arginase 2 to enhance their metabolic fitness in tissues
Reprogramming human T cell function and specificity with non-viral genome targeting
Lipid-derived nanoparticles for immunostimulatory RNA adjuvant delivery