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Sekar Kathiresan

Massachusetts General Hospital · US
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Area of research
Genetics · Surgery
Research interest
Research interests include Genetic Associations and Epidemiology, Lipoproteins and Cardiovascular Health, Genomics and Rare Diseases, and Diabetes, Cardiovascular Risks, and Lipoproteins.
h-index
134
citations
115,452
works
425
NIH funding
primary concept
Medicine
email

Recent publications

South Asian medical cohorts reveal strong founder effects and high rates of homozygosity
Nature Communications 2023cited by 38position: middledoi
Inferring compound heterozygosity from large-scale exome sequencing data
Nature Genetics 2023cited by 34position: middledoi
Association of Habitual Alcohol Intake With Risk of Cardiovascular Disease
JAMA Network Open 2022cited by 426position: middledoi
Large-scale genome-wide association study of coronary artery disease in genetically diverse populations
Nature Medicine 2022cited by 339position: middledoi
Genetic and clinical determinants of abdominal aortic diameter: genome-wide association studies, exome array data and Mendelian randomization study
Human Molecular Genetics 2022cited by 10position: middledoi
A high-resolution HLA reference panel capturing global population diversity enables multi-ancestry fine-mapping in HIV host response
Nature Genetics 2021cited by 183position: middledoi
Clonal hematopoiesis associated with epigenetic aging and clinical outcomes
Aging Cell 2021cited by 130position: middledoi
Chromosome Xq23 is associated with lower atherogenic lipid concentrations and favorable cardiometabolic indices
Nature Communications 2021cited by 51position: middledoi
Author Correction: A structural variation reference for medical and population genetics
Nature 2021cited by 17position: middledoi
A brief history of human disease genetics
Nature 2020cited by 725position: middledoi
Lp(a) (Lipoprotein[a]) Concentrations and Incident Atherosclerotic Cardiovascular Disease
Arteriosclerosis Thrombosis and Vascular Biology 2020cited by 502position: middledoi
Polygenic background modifies penetrance of monogenic variants for tier 1 genomic conditions
Nature Communications 2020cited by 470position: middledoi
Dynamic incorporation of multiple in silico functional annotations empowers rare variant association analysis of large whole-genome sequencing studies at scale
Nature Genetics 2020cited by 289position: middledoi
Analysis of cardiac magnetic resonance imaging in 36,000 individuals yields genetic insights into dilated cardiomyopathy
Nature Communications 2020cited by 264position: middledoi
Landscape of multi-nucleotide variants in 125,748 human exomes and 15,708 genomes
Nature Communications 2020cited by 143position: middledoi
Polygenic Risk Score Identifies Patients at Increased Risk for Abdominal Aortic Aneurysm and May Benefit from Ultrasound Screening
JVS Vascular Science 2020cited by 0position: middledoi
Polygenic Prediction of Weight and Obesity Trajectories from Birth to Adulthood
Cell 2019cited by 815position: lastdoi
Genetic Interleukin 6 Signaling Deficiency Attenuates Cardiovascular Risk in Clonal Hematopoiesis
Circulation 2019cited by 430position: middledoi
Biological and clinical insights from genetics of insomnia symptoms
Nature Genetics 2019cited by 412position: middledoi
Whole-Genome Sequencing to Characterize Monogenic and Polygenic Contributions in Patients Hospitalized With Early-Onset Myocardial Infarction
Circulation 2019cited by 327position: lastdoi
Genome-wide association study of peripheral artery disease in the Million Veteran Program
Nature Medicine 2019cited by 311position: middledoi
Genetics of Common, Complex Coronary Artery Disease
Cell 2019cited by 259position: lastdoi
Genome-wide association analysis of venous thromboembolism identifies new risk loci and genetic overlap with arterial vascular disease
Nature Genetics 2019cited by 255position: middledoi
Association of <i>APOL1</i> Risk Alleles With Cardiovascular Disease in Blacks in the Million Veteran Program
Circulation 2019cited by 52position: middledoi
Genome-wide polygenic scores for common diseases identify individuals with risk equivalent to monogenic mutations
Nature Genetics 2018cited by 3,045position: lastdoi
Multi-ethnic genome-wide association study for atrial fibrillation
Nature Genetics 2018cited by 800position: middledoi
Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program
Nature Genetics 2018cited by 709position: middledoi
Deep-coverage whole genome sequences and blood lipids among 16,324 individuals
Nature Communications 2018cited by 199position: middledoi
Genetic inactivation of ANGPTL4 improves glucose homeostasis and is associated with reduced risk of diabetes
Nature Communications 2018cited by 153position: middledoi
Deep coverage whole genome sequences and plasma lipoprotein(a) in individuals of European and African ancestries
Nature Communications 2018cited by 109position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Amit V. Khera · Institut universitaire de cardiologie et de pneumologie de Québec11 papers (2017–2022)Pradeep Natarajan · Broad Institute10 papers (2016–2020)Alexander G. Bick · Vanderbilt University Medical Center8 papers (2012–2020)Stacey Gabriel · Broad Institute6 papers (2012–2019)Mark Chaffin · Broad Institute5 papers (2017–2020)Patrick T. Ellinor · Icahn School of Medicine at Mount Sinai5 papers (2018–2022)Namrata Gupta · Chandigarh University5 papers (2012–2019)Eric S. Lander · Broad Institute5 papers (2016–2020)Gina M. Peloso · Boston University5 papers (2012–2017)Derek Klarin · Stanford University4 papers (2017–2020)Connor A. Emdin · Massachusetts Institute of Technology4 papers (2017–2017)Minxian Wang · Beijing Institute of Genomics4 papers (2020–2022)Seyedeh M. Zekavat · Broad Institute4 papers (2016–2019)Krishna G. Aragam · Broad Institute4 papers (2018–2022)Wendy S. Post · Bloomberg (United States)3 papers (2014–2020)Daniel J. Rader · RWTH Aachen University3 papers (2012–2020)Stephen S. Rich · Antwerp University Hospital3 papers (2014–2020)Carolina Roselli · Broad Institute3 papers (2017–2019)David Altshuler · Michigan Medicine3 papers (2012–2016)Joel N. Hirschhorn · Harvard University3 papers (2012–2016)
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