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Vivek Subbiah

International Drug Development ·
Area of research
Pulmonary and Respiratory Medicine · Cancer Research
Research interest
Research interests include Cancer Genomics and Diagnostics, Lung Cancer Treatments and Mutations, Sarcoma Diagnosis and Treatment, and Cancer Immunotherapy and Biomarkers.
h-index
78
citations
31,665
works
1,431
NIH funding
primary concept
email

Recent publications

Tumor mutational burden and survival on immune checkpoint inhibition in >8000 patients across 24 cancer types
Journal for ImmunoTherapy of Cancer 2025cited by 36position: middledoi
Cancer treatment paradigms in the precision medicine era
Nature Medicine 2025cited by 8position: firstdoi
Abstract CT109: A first-in-human phase 1 study of LY4050784, an oral, potent, and selective SMARCA2 inhibitor, in patients with advanced solid tumors with <i>SMARCA4</i> alterations (Trial in Progress)
Cancer Research 2025cited by 3position: middledoi
Exploring the pathway: clinical utility and open challenges of targeting BRAF alterations in biliary tract cancers and gastrointestinal malignancies
ESMO Gastrointestinal Oncology 2025cited by 2position: middledoi
Phase Ia/b Multicenter Study of BPM31510IV Targeting Mitochondrial Metabolism/Warburg Effect as Monotherapy and Combination Chemotherapy in Solid Tumor Patients
Cancer Research Communications 2025cited by 2position: firstdoi
Interpreting and integrating genomic tests results in clinical cancer care: Overview and practical guidance
CA A Cancer Journal for Clinicians 2024cited by 57position: middledoi
The ESMO Tumour-Agnostic Classifier and Screener (ETAC-S): a tool for assessing tumour-agnostic potential of molecularly guided therapies and for steering drug development
Annals of Oncology 2024cited by 52position: lastdoi
Durability of Response With Selpercatinib in Patients With <i>RET</i>-Activated Thyroid Cancer: Long-Term Safety and Efficacy From LIBRETTO-001
Journal of Clinical Oncology 2024cited by 39position: middledoi
Leptomeningeal metastatic disease: new frontiers and future directions
Nature Reviews Clinical Oncology 2024cited by 24position: middledoi
Association of Antibody–Drug Conjugate (ADC) Target Expression and Interstitial Lung Disease (ILD) in Non-Small-Cell Lung Cancer (NSCLC): Association or Causation or Neither?
Cancers 2024cited by 8position: middledoi
Open-label, dose-escalation FIGHT-101 study of pemigatinib combined with targeted therapy, chemotherapy, or immunotherapy in patients with advanced malignancies
ESMO Open 2024cited by 7position: middledoi
Dabrafenib plus trametinib in BRAFV600E-mutated rare cancers: the phase 2 ROAR trial
Nature Medicine 2023cited by 287position: firstdoi
Circulating Tumor DNA Enables Sensitive Detection of Actionable Gene Fusions and Rearrangements Across Cancer Types
Clinical Cancer Research 2023cited by 45position: lastdoi
Updated dose escalation results for ReFocus, a first-in-human study of highly selective FGFR2 inhibitor RLY-4008 in cholangiocarcinoma and other solid tumors.
Journal of Clinical Oncology 2023cited by 37position: middledoi
Abstract CT004: Intratumoral (IT) MEDI1191 + durvalumab (D): Update on the first-in-human study in advanced solid tumors
Cancer Research 2023cited by 16position: middledoi
Everolimus in combination with vandetanib in children, adolescents, and young adults: a phase I study
ESMO Open 2023cited by 3position: lastdoi
Tumour-agnostic efficacy and safety of selpercatinib in patients with RET fusion-positive solid tumours other than lung or thyroid tumours (LIBRETTO-001): a phase 1/2, open-label, basket trial
The Lancet Oncology 2022cited by 411position: firstdoi
Dabrafenib plus trametinib in patients with BRAF V600E-mutant anaplastic thyroid cancer: updated analysis from the phase II ROAR basket study
Annals of Oncology 2022cited by 334position: firstdoi
Selpercatinib in Patients With <i>RET</i> Fusion–Positive Non–Small-Cell Lung Cancer: Updated Safety and Efficacy From the Registrational LIBRETTO-001 Phase I/II Trial
Journal of Clinical Oncology 2022cited by 199position: middledoi
FIGHT-101, a first-in-human study of potent and selective FGFR 1-3 inhibitor pemigatinib in pan-cancer patients with FGF/FGFR alterations and advanced malignancies
Annals of Oncology 2022cited by 195position: firstdoi
Safety and efficacy of pralsetinib in RET fusion–positive non-small-cell lung cancer including as first-line therapy: update from the ARROW trial
Annals of Oncology 2022cited by 175position: middledoi
Clinical Activity of Mitogen-Activated Protein Kinase–Targeted Therapies in Patients With Non–V600 BRAF-Mutant Tumors
JCO Precision Oncology 2022cited by 48position: middledoi
The Armed Conflict and the Impact on Patients With Cancer in Ukraine: Urgent Considerations
JCO Global Oncology 2022cited by 46position: middledoi
A phase 1b multitumor cohort study of cabozantinib plus atezolizumab in advanced solid tumors (COSMIC-021): Results of the colorectal cancer cohort.
Journal of Clinical Oncology 2022cited by 19position: middledoi
Pralsetinib for RET fusion-positive non-small-cell lung cancer (ARROW): a multi-cohort, open-label, phase 1/2 study
The Lancet Oncology 2021cited by 441position: lastdoi
Real-world application of tumor mutational burden-high (TMB-high) and microsatellite instability (MSI) confirms their utility as immunotherapy biomarkers
ESMO Open 2021cited by 350position: middledoi
Pralsetinib for patients with advanced or metastatic RET-altered thyroid cancer (ARROW): a multi-cohort, open-label, registrational, phase 1/2 study
The Lancet Diabetes & Endocrinology 2021cited by 347position: firstdoi
COVID-19 vaccine guidance for patients with cancer participating in oncology clinical trials
Nature Reviews Clinical Oncology 2021cited by 140position: lastdoi
Intracranial Efficacy of Selpercatinib in <i>RET</i> Fusion-Positive Non–Small Cell Lung Cancers on the LIBRETTO-001 Trial
Clinical Cancer Research 2021cited by 135position: firstdoi
ESMO recommendations on the standard methods to detect RET fusions and mutations in daily practice and clinical research
Annals of Oncology 2021cited by 118position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Razelle Kurzrock · Froedtert Hospital13 papers (2014–2025)Funda Meric‐Bernstam · Breast Cancer Care13 papers (2014–2023)Filip Jankú · The University of Texas MD Anderson Cancer Center11 papers (2014–2020)Giuseppe Curigliano · Istituti di Ricovero e Cura a Carattere Scientifico11 papers (2019–2025)David S. Hong · The University of Texas MD Anderson Cancer Center10 papers (2015–2020)Siqing Fu · The University of Texas MD Anderson Cancer Center9 papers (2014–2020)Alexander Drilon · Université Grenoble Alpes9 papers (2018–2024)Apostolia M. Tsimberidou · The University of Texas MD Anderson Cancer Center8 papers (2014–2020)Justin F. Gainor · Harvard University8 papers (2018–2021)Sarina A. Piha‐Paul · The University of Texas MD Anderson Cancer Center8 papers (2015–2023)Kenneth R. Hess · The University of Texas MD Anderson Cancer Center7 papers (2015–2020)Aung Naing · The University of Texas MD Anderson Cancer Center7 papers (2015–2020)Antoîne Italiano · Institut Bergonié6 papers (2015–2023)Antoine Hollebecque · Institut Gustave Roussy6 papers (2015–2023)Lori J. Wirth · Harvard University6 papers (2018–2024)Benjamin Solomon · Peter MacCallum Cancer Centre5 papers (2018–2024)Elena Garralda · University College London5 papers (2018–2024)Daniel D. Karp · The University of Texas MD Anderson Cancer Center5 papers (2015–2020)Marcia S. Brose · Thomas Jefferson University5 papers (2018–2024)Zev A. Wainberg · UCLA Medical Center5 papers (2019–2023)