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Apostolia M. Tsimberidou

The University of Texas MD Anderson Cancer Center · US
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Area of research
Oncology · Cancer Research
Research interest
Research interests include Cancer Genomics and Diagnostics, CAR-T cell therapy research, Lung Cancer Treatments and Mutations, and Colorectal Cancer Treatments and Studies.
h-index
75
citations
23,236
works
996
NIH funding
primary concept
email

Recent publications

Botensilimab (Fc-enhanced anti–cytotoxic lymphocyte-association protein-4 antibody) Plus Balstilimab (anti–PD-1 antibody) in Patients With Relapsed/Refractory Metastatic Sarcomas
Journal of Clinical Oncology 2025cited by 17position: lastdoi
1600O Efficacy and safety of IMA203, a PRAME-directed T-cell receptor (TCR) T-cell therapy, in patients with previously treated advanced or metastatic uveal melanoma from a phase I trial
Annals of Oncology 2025cited by 4position: middledoi
Phase 1 clinical update of IMA203, an autologous TCR-T targeting PRAME in patients with PD1 refractory metastatic melanoma.
Journal of Clinical Oncology 2025cited by 2position: middledoi
Botensilimab plus balstilimab in relapsed/refractory microsatellite stable metastatic colorectal cancer: a phase 1 trial
Nature Medicine 2024cited by 97position: middledoi
Pertuzumab Plus Trastuzumab in Patients With Endometrial Cancer With <i>ERBB2/3</i> Amplification, Overexpression, or Mutation: Results From the TAPUR Study
JCO Precision Oncology 2023cited by 19position: middledoi
LBA-4 Results from an expanded phase 1 trial of botensilimab (BOT), a multifunctional anti-CTLA-4, plus balstilimab (BAL; anti-PD-1) for metastatic heavily pretreated microsatellite stable colorectal cancer (MSS CRC)
Annals of Oncology 2023cited by 16position: middledoi
Review of precision cancer medicine: Evolution of the treatment paradigm
Cancer Treatment Reviews 2020cited by 738position: firstdoi
Phase 2 study of pembrolizumab in patients with advanced rare cancers
Journal for ImmunoTherapy of Cancer 2020cited by 130position: middledoi
Transcriptomics and solid tumors: The next frontier in precision cancer medicine
Seminars in Cancer Biology 2020cited by 105position: firstdoi
Phase I studies of vorinostat with ixazomib or pazopanib imply a role of antiangiogenesis-based therapy for TP53 mutant malignancies
Scientific Reports 2020cited by 20position: middledoi
Genomic and transcriptomic profiling expands precision cancer medicine: the WINTHER trial
Nature Medicine 2019cited by 593position: middledoi
Long-term overall survival and prognostic score predicting survival: the IMPACT study in precision medicine
Journal of Hematology & Oncology 2019cited by 81position: firstdoi
Phase 1 Dose Escalation Study of the Allosteric AKT Inhibitor BAY 1125976 in Advanced Solid Cancer—Lack of Association between Activating AKT Mutation and AKT Inhibition-Derived Efficacy
Cancers 2019cited by 13position: middledoi
Outcome analysis of Phase I trial patients with metastatic<i>KRAS</i>and/or<i>TP53</i>mutant non-small cell lung cancer
Oncotarget 2018cited by 11position: middledoi
Incidence of immune-related adverse events and its association with treatment outcomes: the MD Anderson Cancer Center experience
Investigational New Drugs 2017cited by 182position: middledoi
Liquid biopsies of plasma exosomal nucleic acids, plasma cell-free DNA, and survival of patients with advanced cancers.
Journal of Clinical Oncology 2017cited by 0position: middledoi
Standards and Guidelines for the Interpretation and Reporting of Sequence Variants in Cancer
Journal of Molecular Diagnostics 2016cited by 1,981position: middledoi
Phase IB Study of Vemurafenib in Combination with Irinotecan and Cetuximab in Patients with Metastatic Colorectal Cancer with <i>BRAF</i> V600E Mutation
Cancer Discovery 2016cited by 218position: middledoi
<i>BRAF</i> Mutation Testing in Cell-Free DNA from the Plasma of Patients with Advanced Cancers Using a Rapid, Automated Molecular Diagnostics System
Molecular Cancer Therapeutics 2016cited by 78position: middledoi
Phase I dose-escalation study of the mTOR inhibitor sirolimus and the HDAC inhibitor vorinostat in patients with advanced malignancy
Oncotarget 2016cited by 51position: middledoi
Actionable mutations in plasma cell-free DNA in patients with advanced cancers referred for experimental targeted therapies
Oncotarget 2015cited by 93position: middledoi
Challenges in initiating and conducting personalized cancer therapy trials: perspectives from WINTHER, a Worldwide Innovative Network (WIN) Consortium trial
Annals of Oncology 2015cited by 75position: middledoi
Phase I study of pazopanib and vorinostat: a therapeutic approach for inhibiting mutant p53-mediated angiogenesis and facilitating mutant p53 degradation
Annals of Oncology 2015cited by 73position: middledoi
Xilonix, a novel true human antibody targeting the inflammatory cytokine interleukin-1 alpha, in non-small cell lung cancer
Investigational New Drugs 2015cited by 69position: middledoi
Gene and cell therapy for pancreatic cancer
Expert Opinion on Biological Therapy 2015cited by 23position: lastdoi
Assessing PIK3CA and PTEN in Early-Phase Trials with PI3K/AKT/mTOR Inhibitors
Cell Reports 2014cited by 237position: middledoi
MABp1, a first-in-class true human antibody targeting interleukin-1α in refractory cancers: an open-label, phase 1 dose-escalation and expansion study
The Lancet Oncology 2014cited by 194position: middledoi
Identification of novel therapeutic targets in the PI3K/AKT/mTOR pathway in hepatocellular carcinoma using targeted next generation sequencing
Oncotarget 2014cited by 94position: middledoi
Analysis of 1,115 Patients Tested for <i>MET</i> Amplification and Therapy Response in the MD Anderson Phase I Clinic
Clinical Cancer Research 2014cited by 78position: middledoi
Unique molecular signatures as a hallmark of patients with metastatic breast cancer: Implications for current treatment paradigms
Oncotarget 2014cited by 59position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Filip Jankú · The University of Texas MD Anderson Cancer Center16 papers (2012–2020)Siqing Fu · The University of Texas MD Anderson Cancer Center15 papers (2012–2020)Razelle Kurzrock · Froedtert Hospital15 papers (2012–2020)David S. Hong · The University of Texas MD Anderson Cancer Center14 papers (2012–2020)Aung Naing · The University of Texas MD Anderson Cancer Center13 papers (2012–2020)Sarina A. Piha‐Paul · The University of Texas MD Anderson Cancer Center13 papers (2012–2020)Jennifer J. Wheler · The University of Texas MD Anderson Cancer Center10 papers (2012–2019)Funda Meric‐Bernstam · Breast Cancer Care9 papers (2014–2018)Gerald S. Falchook · Sarah Cannon Research Institute8 papers (2012–2019)Vivek Subbiah · International Drug Development8 papers (2014–2020)Ralph Zinner · University of Kentucky6 papers (2014–2016)Kenneth R. Hess · The University of Texas MD Anderson Cancer Center5 papers (2014–2020)Russell R. Broaddus · L'Alliance Boviteq4 papers (2014–2020)Stacy Moulder · Eli Lilly (United States)4 papers (2012–2019)Scott Kopetz · The University of Texas MD Anderson Cancer Center4 papers (2015–2020)Daniel D. Karp · The University of Texas MD Anderson Cancer Center4 papers (2015–2020)Rajyalakshmi Luthra · The University of Texas MD Anderson Cancer Center3 papers (2012–2015)Michael J. Overman · The University of Texas MD Anderson Cancer Center3 papers (2015–2020)Richard L. Schilsky · American Society of Clinical Oncology3 papers (2015–2023)Ahmed O. Kaseb · The University of Texas MD Anderson Cancer Center2 papers (2014–2016)
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