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Jun Lai

Xi'an Jiaotong University · CN
Area of research
Infectious Diseases · Virology
Research interest
Research interests include HIV Research and Treatment, HIV/AIDS drug development and treatment, HIV/AIDS Research and Interventions, and Immune Cell Function and Interaction.
h-index
30
citations
6,268
works
60
NIH funding
primary concept
Medicine
email

Recent publications

Proviruses in CD4 <sup>+</sup> T cells reactive to autologous antigens contribute to nonsuppressible HIV-1 viremia
Science Translational Medicine 2025cited by 3position: middledoi
Superinfection promotes replication and diversification of defective HIV-1 proviruses in people with non-suppressible viraemia
Nature Microbiology 2025cited by 2position: middledoi
Age-dependent interaction between serum zinc and triglyceride-glucose index among American adults: National Health and Nutrition Examination Survey
Frontiers in Nutrition 2025cited by 2position: firstdoi
Bispecific antibodies promote natural killer cell-mediated elimination of HIV-1 reservoir cells
Nature Immunology 2024cited by 42position: middledoi
CD4+ T cells with latent HIV-1 have reduced proliferative responses to T cell receptor stimulation
The Journal of Experimental Medicine 2024cited by 14position: middledoi
Cognate antigen engagement induces HIV-1 expression in latently infected CD4+ T cells from people on long-term antiretroviral therapy
Immunity 2024cited by 10position: middledoi
The latent reservoir of inducible, infectious HIV-1 does not decrease despite decades of antiretroviral therapy
Journal of Clinical Investigation 2023cited by 127position: middledoi
Clonally expanded HIV-1 proviruses with 5′-leader defects can give rise to nonsuppressible residual viremia
Journal of Clinical Investigation 2023cited by 90position: middledoi
Measuring the latent reservoir for HIV-1: Quantification bias in near full-length genome sequencing methods
PLoS Pathogens 2022cited by 55position: middledoi
Differential decay of intact and defective proviral DNA in HIV-1–infected individuals on suppressive antiretroviral therapy
JCI Insight 2020cited by 249position: middledoi
Antigen-driven clonal selection shapes the persistence of HIV-1–infected CD4+ T cells in vivo
Journal of Clinical Investigation 2020cited by 175position: middledoi
Allogeneic bone marrow transplantation with post-transplant cyclophosphamide for patients with HIV and haematological malignancies: a feasibility study
The Lancet HIV 2020cited by 48position: middledoi
HSF1 inhibition attenuates HIV-1 latency reversal mediated by several candidate LRAs In Vitro and Ex Vivo
Proceedings of the National Academy of Sciences 2020cited by 40position: middledoi
HIV-1 latent reservoir size and diversity are stable following brief treatment interruption
Journal of Clinical Investigation 2018cited by 111position: middledoi
The role of CD32 during HIV-1 infection
Nature 2018cited by 49position: middledoi
Reduced Frequency of Cells Latently Infected With Replication-Competent Human Immunodeficiency Virus-1 in Virally Suppressed Individuals Living in Rakai, Uganda
Clinical Infectious Diseases 2017cited by 30position: middledoi
Defective proviruses rapidly accumulate during acute HIV-1 infection
Nature Medicine 2016cited by 770position: middledoi
Broad CTL response is required to clear latent HIV-1 due to dominance of escape mutations
Nature 2015cited by 500position: middledoi
Measuring the Frequency of Latent HIV-1 in Resting CD4+ T Cells Using a Limiting Dilution Coculture Assay
Methods in molecular biology 2015cited by 92position: middledoi
Replication-Competent Noninduced Proviruses in the Latent Reservoir Increase Barrier to HIV-1 Cure
Cell 2013cited by 1,468position: middledoi
Comparative Analysis of Measures of Viral Reservoirs in HIV-1 Eradication Studies
PLoS Pathogens 2013cited by 576position: middledoi
Rapid Quantification of the Latent Reservoir for HIV-1 Using a Viral Outgrowth Assay
PLoS Pathogens 2013cited by 246position: middledoi
A quantitative basis for antiretroviral therapy for HIV-1 infection
Nature Medicine 2012cited by 168position: middledoi
HIV-1 DNA Is Detected in Bone Marrow Populations Containing CD4+ T Cells but Is not Found in Purified CD34+ Hematopoietic Progenitor Cells in Most Patients on Antiretroviral Therapy
The Journal of Infectious Diseases 2012cited by 117position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Robert F. Siliciano · University of Baltimore20 papers (2012–2025)Janet D. Siliciano · Howard Hughes Medical Institute19 papers (2012–2025)Steven G. Deeks · University of California, San Francisco8 papers (2013–2024)Francesco R. Simonetti · Johns Hopkins University8 papers (2018–2025)Subul Beg · Johns Hopkins University7 papers (2018–2025)Rebecca Hoh · World Wide Web Consortium6 papers (2013–2024)Fengting Wu · Johns Hopkins University5 papers (2020–2025)Pablo Tebas · Presbyterian Hospital4 papers (2018–2024)Luis J. Montaner · The Wistar Institute4 papers (2018–2025)Gregory M. Laird · CCC Diagnostics (United States)4 papers (2013–2020)Jennifer A. White · Palo Alto University4 papers (2018–2025)Milica Moskovljevic · Johns Hopkins Medicine4 papers (2024–2025)Nathan L. Board · Cornell University3 papers (2024–2025)Anushka Singhal · Johns Hopkins Medicine3 papers (2024–2025)Filippo Dragoni · Johns Hopkins Medicine3 papers (2024–2025)Hao Zhang · The First People's Hospital of Shunde3 papers (2012–2025)S. Alireza Rabi · University Health Network3 papers (2012–2013)Sarah B. Laskey · 23andMe (United States)2 papers (2013–2016)Adam A. Capoferri · Johns Hopkins University2 papers (2016–2017)Jeanne Keruly · University of Alabama at Birmingham2 papers (2017–2025)