Area of research
Oncology · Immunology
Research interest
Research interests include Biology, Interferon, ISG15, Immunity, Inflammation, and STAT2.
The immune factors driving DNA methylation variation in human blood
A partial form of inherited human USP18 deficiency underlies infection and inflammation
A loss-of-function <i>IFNAR1</i> allele in Polynesia underlies severe viral diseases in homozygotes
Herpes simplex encephalitis in a patient with a distinctive form of inherited IFNAR1 deficiency
Tuberculosis and impaired IL-23–dependent IFN-γ immunity in humans homozygous for a common <i>TYK2</i> missense variant
Parallel derivation of isogenic human primed and naive induced pluripotent stem cells
STAT2 is an essential adaptor in USP18-mediated suppression of type I interferon signaling
Human USP18 deficiency underlies type 1 interferonopathy leading to severe pseudo-TORCH syndrome
Mycolactone subverts immunity by selectively blocking the Sec61 translocon
Human intracellular ISG15 prevents interferon-α/β over-amplification and auto-inflammation
Tyk2 and Stat3 Regulate Brown Adipose Tissue Differentiation and Obesity