Sabrina Diano

Suppression of endothelial ceramide de novo biosynthesis by Nogo-B contributes to cardiometabolic diseases

Abstract A005: An Iron-regulated Signalling Pathway Controls Adipose Browning and Cancer Cachexia

Skeletal muscle TET3 promotes insulin resistance through destabilisation of PGC-1α

Prostaglandin in the ventromedial hypothalamus regulates peripheral glucose metabolism.

Hepatic TET3 contributes to type-2 diabetes by inducing the HNF4α fetal isoform

Ghrelin

Fatty acid amide hydrolase ablation promotes ectopic lipid storage and insulin resistance due to centrally mediated hypothyroidism

Diano S , Liu ZW, Jeong JK, Dietrich MO, Ruan HB, Kim E, Suyama S, Kelly K, Gyengesi E, Arbiser JL, Belsham DD, Sarruf DA, Schwartz MW, Bennett A, Shanabrough M, Mobbs CV, Yang X, Gao XB, Horvath TL (2011) Peroxisome proliferation-related hypothalamic control of ROS sets melanocortin tone and feedin

Wallingford N, Perroud B, Gao Q, Coppola A, Gyengesi E, Liu ZW, Gao XB, Diament A, Haus KA, Shariat-Madar Z, Mahdi F, Wardlaw SL, Schmaier AH, Warden CH,  Diano S . (2009)  Prolylcarboxypeptidase regulates food intake by inactivating alpha-MSH in rodents.   J Clin Invest . 119(8):2291-303.

Andrews ZB, Liu ZW, Wallingford N, Erion DM, Borok E, Friedman JM, Tschoep MH, Shanabrough M, Cline GM, Shulman GI, Coppola A, Gao XB, Horvath TL,  Diano S  (2008) UCP2 mediates ghrelin’s action on NPY/AgRP neurons.  Nature   454 ( 7206 ): 846-51 .

Coppola A, Liu ZW, Andrews ZB, Paradis E, Roy MC, Friedman JM, Ricquier D, Richard D, Horvath TL, Gao XB,  Diano S.   (2007) A central thermogenic-like mechanism in feeding regulation: an interplay between arcuate nucleus T3 and UCP2.  Cell Metabolism  5:21-33 .

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