Area of research
Oncology · Immunology
Research interest
Research interests include CAR-T cell therapy research, T-cell and B-cell Immunology, Cancer Immunotherapy and Biomarkers, and Pancreatic and Hepatic Oncology Research.
Harnessing lipid-driven immunometabolic pathways in omental metastases to enhance immunotherapy in patients with ovarian cancer
Enhanced mutanome analysis towards the induction of neoepitope-reactive T-cell responses for personalized immunotherapy of pancreatic cancer
Single-cell chromatin landscape and DNA methylation patterns reveal shared molecular programs in human tumor and non-tumor tissue CCR8 <sup>+</sup> Treg cells
optiPRM: A Targeted Immunopeptidomics LC-MS Workflow With Ultra-High Sensitivity for the Detection of Mutation-Derived Tumor Neoepitopes From Limited Input Material
T-Cell-Based Platform for Functional Screening of T-Cell Receptors Identified in Single-Cell RNA Sequencing Data Sets of Tumor-Infiltrating T Cells
Transcriptome-based identification of tumor-reactive and bystander CD8 <sup>+</sup> T cell receptor clonotypes in human pancreatic cancer
Identification of TRDV-TRAJ V domains in human and mouse T-cell receptor repertoires
Using combined single-cell gene expression, TCR sequencing and cell surface protein barcoding to characterize and track CD4+ T cell clones from murine tissues
Human Retrotransposons and the Global Shutdown of Homeostatic Innate Immunity by Oncolytic Parvovirus H-1PV in Pancreatic Cancer
Deep molecular characterization linked to drug response profiling of pancreatic ductal adenocarcinoma using patient-derived organoids
Proimmunogenic impact of MEK inhibition synergizes with agonist anti-CD40 immunostimulatory antibodies in tumor therapy
Phosphoproteomics of CD2 signaling reveals AMPK-dependent regulation of lytic granule polarization in cytotoxic T cells
Actinin-4 splice variant - a complementary diagnostic and prognostic marker of pancreatic neuroendocrine neoplasms
A bicistronic vector backbone for rapid seamless cloning and chimerization of αβT-cell receptor sequences
Cancer Neoepitopes for Immunotherapy: Discordance Between Tumor-Infiltrating T Cell Reactivity and Tumor MHC Peptidome Display
Phosphoproteomics of CD2 signaling reveals an AMPK-dependent regulation of lytic granule polarization in cytotoxic T cells
Epithelial-specific E3 ligase CBLc regulates differentiation and motility of pancreatic cancer cells
Mutational profile in IPMN subtypes
Identification of a tumor-reactive T-cell repertoire in the immune infiltrate of patients with resectable pancreatic ductal adenocarcinoma
Establishment and Characterization of a Novel Cell Line, ASAN-PaCa, Derived From Human Adenocarcinoma Arising in Intraductal Papillary Mucinous Neoplasm of the Pancreas
Abstract IA46: Towards implementation of T-cell therapy in pancreatic cancer
T-cell therapy of pancreatic cancer