Area of research
Cancer Research · Pulmonary and Respiratory Medicine
Research interest
Research interests include Protease and Inhibitor Mechanisms, Peptidase Inhibition and Analysis, Chronic Obstructive Pulmonary Disease (COPD) Research, and Blood Coagulation and Thrombosis Mechanisms.
Distinct metabolic responses to heme in inflammatory human and mouse macrophages – Role of nitric oxide
Alpha-1-antitrypsin-deficiency is associated with lower cardiovascular risk: an approach based on federated learning
A Morphomolecular Approach to Alveolar Capillary Dysplasia
Latest developments in metal complexes as anticancer agents
Hepatobiliary phenotypes of adults with alpha-1 antitrypsin deficiency
Matrix metalloproteinase‐13 is fully activated by neutrophil elastase and inactivates its serpin inhibitor, alpha‐1 antitrypsin: Implications for osteoarthritis
Potential Roles of Acute Phase Proteins in Cancer: Why Do Cancer Cells Produce or Take Up Exogenous Acute Phase Protein Alpha1-Antitrypsin?
Liver Phenotypes of European Adults Heterozygous or Homozygous for Pi∗Z Variant of AAT (Pi∗MZ vs Pi∗ZZ genotype) and Noncarriers
TLR4 Signaling by Heme and the Role of Heme-Binding Blood Proteins
Protocol for the EARCO Registry: a pan-European observational study in patients with α<sub>1</sub>-antitrypsin deficiency
Novel Liquid Biomarker Panels for A Very Early Response Capturing of NSCLC Therapies in Advanced Stages
Liver Fibrosis and Metabolic Alterations in Adults With alpha-1-antitrypsin Deficiency Caused by the Pi*ZZ Mutation
Clinical Significance of SERPINA1 Gene and Its Encoded Alpha1-antitrypsin Protein in NSCLC
Heterozygous carriage of the alpha1-antitrypsin Pi*Z variant increases the risk to develop liver cirrhosis
Liver – master and servant of serum proteome
Ultra-early response capturing in the treatment of non-squamous NSCLC using diffusion-weighted MRI: A prospective multicenter study
Heme as a Target for Therapeutic Interventions
Prevalence of comorbidities in COPD patients by disease severity in a German population
Benefits of High-Intensity Exercise Training to Patients with Chronic Obstructive Pulmonary Disease: A Controlled Study
Alpha1-antitrypsin binds hemin and prevents oxidative activation of human neutrophils: putative pathophysiological significance
Gene and miRNA expression profiles in PBMCs from patients with severe and mild emphysema and PiZZ alpha1-antitrypsin deficiency
Phosphocholine-Modified Macromolecules and Canonical Nicotinic Agonists Inhibit ATP-Induced IL-1β Release
A high frequency of MDSCs in sepsis patients, with the granulocytic subtype dominating in gram-positive cases
Benefits of whole body vibration training in patients hospitalised for COPD exacerbations - a randomized clinical trial
Tumor cell‐expressed SerpinB2 is present on microparticles and inhibits metastasis
α-1-Antitrypsin (AAT)–modified donor cells suppress GVHD but enhance the GVL effect: a role for mitochondrial bioenergetics
CD14hiHLA-DRdim macrophages, with a resemblance to classical blood monocytes, dominate inflamed mucosa in Crohn's disease
Role of IL-18 in Second-Hand Smoke–Induced Emphysema
Plexiform vasculopathy of severe pulmonary arterial hypertension and microRNA expression