Area of research
Pulmonary and Respiratory Medicine · Genetics
Research interest
Research interests include Chronic Obstructive Pulmonary Disease (COPD) Research, Genetic Associations and Epidemiology, Respiratory Support and Mechanisms, and Asthma and respiratory diseases.
Sequencing in over 50,000 cases identifies coding and structural variation underlying atrial fibrillation risk
A Multidimensional Diagnostic Approach for Chronic Obstructive Pulmonary Disease
Chronic Obstructive Pulmonary Disease Exacerbations Increase the Risk of Subsequent Cardiovascular Events: A Longitudinal Analysis of the COPDGene Study
Differential Association of COPD Subtypes With Cardiovascular Events and COPD Exacerbations
Rare variant contribution to the heritability of coronary artery disease
Genome-wide association meta-analysis identifies 17 loci associated with nonalcoholic fatty liver disease
Multi-ancestry genome-wide study identifies effector genes and druggable pathways for coronary artery calcification
Multi-ancestry transcriptome-wide association analyses yield insights into tobacco use biology and drug repurposing
Evaluating the use of blood pressure polygenic risk scores across race/ethnic background groups
Early Evidence of Chronic Obstructive Pulmonary Disease Obscured by Race-Specific Prediction Equations
Whole-genome sequencing uncovers two loci for coronary artery calcification and identifies ARSE as a regulator of vascular calcification
Race-Specific Spirometry Equations Do Not Improve Models of Dyspnea and Quantitative Chest CT Phenotypes
Prevalence of abnormal spirometry in individuals with a smoking history and no known obstructive lung disease
Type 2 Diabetes Modifies the Association of CAD Genomic Risk Variants With Subclinical Atherosclerosis
Use of the Spirometric “Fixed-Ratio” Underdiagnoses COPD in African-Americans in a Longitudinal Cohort Study
Assessing the contribution of rare variants to complex trait heritability from whole-genome sequence data
Rare genetic variants explain missing heritability in smoking
Pulmonary Arterial Pruning and Longitudinal Change in Percent Emphysema and Lung Function
Longitudinal Association Between Muscle Loss and Mortality in Ever Smokers
Model-based assessment of replicability for genome-wide association meta-analysis
Respiratory exacerbations are associated with muscle loss in current and former smokers
Small Airway Disease and Emphysema Are Associated with Future Exacerbations in Smokers with CT-derived Bronchiectasis and COPD: Results from the COPDGene Cohort
Emphysema Progression and Lung Function Decline Among Angiotensin Converting Enzyme Inhibitors and Angiotensin-Receptor Blockade Users in the COPDGene Cohort
Expanding the genetic architecture of nicotine dependence and its shared genetics with multiple traits
Association studies of up to 1.2 million individuals yield new insights into the genetic etiology of tobacco and alcohol use
Arterial Vascular Pruning, Right Ventricular Size, and Clinical Outcomes in Chronic Obstructive Pulmonary Disease. A Longitudinal Observational Study
Clinical Epidemiology of COPD
Latent autoimmunity across disease-specific boundaries in at-risk first-degree relatives of SLE and RA patients
Blood eosinophil count thresholds and exacerbations in patients with chronic obstructive pulmonary disease
The triglyceride to high-density lipoprotein cholesterol (TG/HDL-C) ratio as a predictor of insulin resistance, β-cell function, and diabetes in Hispanics and African Americans