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Jonathan M. Tsai

Broad Institute ·
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Area of research
Public Health, Environmental and Occupational Health · Molecular Biology
Research interest
Research interests include Acute Lymphoblastic Leukemia research, Acute Myeloid Leukemia Research, Lymphoma Diagnosis and Treatment, and Protein Degradation and Inhibitors.
h-index
20
citations
5,817
works
63
NIH funding
primary concept
email

Recent publications

Targeted protein degradation: from mechanisms to clinic
Nature Reviews Molecular Cell Biology 2024cited by 331position: firstdoi
Template-assisted covalent modification underlies activity of covalent molecular glues
Nature Chemical Biology 2024cited by 83position: middledoi
The human E3 ligase RNF185 is a regulator of the SARS-CoV-2 envelope protein
iScience 2023cited by 8position: middledoi
Menin Inhibitor Induced Menin Protein Degradation Contributes to Menin Inhibitor Efficacy
Blood 2023cited by 2position: middledoi
<i>Dnmt3a</i> -mutated clonal hematopoiesis promotes osteoporosis
The Journal of Experimental Medicine 2021cited by 155position: middledoi
Small-molecule-induced polymerization triggers degradation of BCL6
Nature 2020cited by 267position: middledoi
Complex mammalian-like haematopoietic system found in a colonial chordate
Nature 2018cited by 132position: middledoi
Wnt/β-catenin signaling regulates ependymal cell development and adult homeostasis
Proceedings of the National Academy of Sciences 2018cited by 58position: middledoi
PD-1 expression by tumour-associated macrophages inhibits phagocytosis and tumour immunity
Nature 2017cited by 2,252position: middledoi
Engagement of MHC class I by the inhibitory receptor LILRB1 suppresses macrophages and is a target of cancer immunotherapy
Nature Immunology 2017cited by 555position: middledoi
Coral cell separation and isolation by fluorescence-activated cell sorting (FACS)
BMC Cell Biology 2017cited by 70position: middledoi
Mapping the Pairwise Choices Leading from Pluripotency to Human Bone, Heart, and Other Mesoderm Cell Types
Cell 2016cited by 509position: middledoi
Engineering high-affinity PD-1 variants for optimized immunotherapy and immuno-PET imaging
Proceedings of the National Academy of Sciences 2015cited by 350position: middledoi
Epidermal Growth-Factor – Induced Transcript Isoform Variation Drives Mammary Cell Migration
PLoS ONE 2013cited by 17position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Irving L. Weissman · Stanford University5 papers (2015–2018)Benjamin L. Ebert · Harvard University4 papers (2020–2024)Radosław P. Nowak · University of Bonn4 papers (2020–2024)Eric S. Fischer · Harvard University4 papers (2020–2024)Aaron M. Ring · Fred Hutch Cancer Center3 papers (2015–2017)Benson M. George · Boston Children's Hospital3 papers (2016–2017)Sydney Gordon · California University of Pennsylvania3 papers (2015–2017)Katherine A. Donovan · Harvard University3 papers (2020–2023)Roy L. Maute · Heron Therapeutics (United States)3 papers (2015–2017)Rahul Sinha · Maulana Azad National Institute of Technology3 papers (2016–2018)Benyamin Rosental · California Institute for Regenerative Medicine3 papers (2017–2018)Nathaniel B. Fernhoff · Menlo School2 papers (2016–2017)Amira Barkal · Heron Therapeutics (United States)2 papers (2016–2017)Adam S. Sperling · Harvard University2 papers (2020–2023)Daniel Corey · Rapt Therapeutics (United States)2 papers (2017–2018) · 2 papers (2020–2023)Charles Zou · Yale Cancer Center2 papers (2020–2023)Shourya S. Roy Burman · Dana-Farber Cancer Institute2 papers (2020–2023) · 2 papers (2020–2023)Nan Ring · California Institute for Regenerative Medicine2 papers (2015–2017)
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